Knowde Enhanced TDS
Identification & Functionality
- Ingredient Origin
- Food Ingredients Functions
- Pharma & Nutraceuticals Functions
- Latin Name
- Auricuralia Auricular
- Active Ingredients
- Polysacchrides
- Part used
- Fruit body
- Product Families
- Chemical constituents of Black fungus Powder Extract
Black fungus extract rich black fungus polysaccharide by L - fucose, L - arabinose, D - xylose, D - mannose, d-glucose and glucuronic acid, monosaccharide composition.
Features & Benefits
- Benefit Claims (Health)
- Labeling Claims
- Food Ingredients Features
- Product Highlight
A Black Fungus has a spherical, pitch black head with two glowing yellow, beady eyes. It wears a round, purple cap on its head that sports two black, angular spirals on its front. It also seems to wear a navy blue smock that completely covers its legs and thin, fingerless arms. Its Heartless emblem is present on the front of this smock. The Black Fungus's name references its dark coloration, as well as Fungi, a biological kingdom that contains organisms such as mushrooms and truffles.
- Benefits of taking Black fungus Powder Extract supplements
Traditional Chinese medicine
Chinese medicine believes that black fungus sweet nature, cooling blood, hemostasis, attending hemoptysis, hematemesis, nose bleeding, bloody diarrhea, bleeding, bleeding hemorrhoids, constipation, blood, etc.
Modern Medicine
Black fungus Powder Extract and Hypocholesterolemic effects
>Hypocholesterolemic effects of Auricularia auricula ethanol extract in ICR mice fed a cholesterol-enriched diet.
（Source-State Key Laboratory of Food Science and Technology, Nanchang University, Nanchang, 330031 China）
Abstract
The cholesterol-lowering properties of Auricularia auricula are commonly attributed to the presence of polysaccharides based on previous research. The present study was designed to investigate the effects of ethanol extract of A. auricula (AAE) on hypercholesterolemia in ICR mice. AAE contained more than 16% (g/g) polyphenolic compounds, excluding other interfering factors such as polysaccharides, water-soluble fiber and protein. Thirty-six mice were randomly assigned to three groups (n = 12). The experimental group was fed cholesterol-enriched diet (CED) with oral administration of AAE (150 mg/kg/d b.w.) for 8-week, normal control group and CED control group received either a regular diet (RD) or CED along with oral administration of equal volume distilled water. Serum lipid profiles and antioxidant status were measured in addition to fecal neutral cholesterol and bile acids. AAE showed a remarkable hypocholesterolemic effect, improving antioxidant status, decreasing the level of total cholesterol and atherosclerosis index, increasing the level of high-density lipoprotein cholesterol and fecal excretion of bile acids. No apparent effects on serum triglycerides, low-density lipoprotein cholesterol, fecal excretion of neutral cholesterol and feeding efficiency were observed among all groups. These results indicated that A. auricula functional components, which prevented hypercholesterolemia contained polyphenolic compounds, in addition to polysaccharides.
Black fungus Powder Extract and antioxidant
Carboxymethylation of polysaccharides from Auricularia auricula and their antioxidant activities in vitro.
(Source-School of Chemistry and Chemical Engineering, Jiangsu University, Xuefu Rd. 301, Zhenjiang 212013, China.)
Abstract
The chemical carboxymethylated polysaccharide (CMAAP), which is derived from the poorly water-soluble, crude polysaccharide from Auricularia auricula (AAP), was prepared. The degree of substitution of CMAAP was 0.857, and its solubility in water reached 0.6 mg/mL, much higher than that of AAP (0.1 mg/mL). One fraction, CMAAP22, was purified. Chemical analysis indicated that CMAAP22 was composed of mannose and glucose in a ratio of 1.06:1 with a molecular weight of 3.4 × 10(6)Da. IR spectra and (13)C NMR spectra indicated that the C2, C4 and C6 positions were partially substituted by -CH(2)COOH. AFM revealed that CMAAP22 was spherical particle structure with a diameter of 80-300 nm. Moreover, the antioxidant activity of CMAAP22 was improved, nearly twice as much as that of the AAP, especially in the scavenging of DPPH and ABTS+.
Black fungus Powder Extract and antiviral activity
>In vitro antiviral activity of sulfated Auricularia auricula polysaccharides.
Nguyen TL, Chen J, Hu Y, Wang D, Fan Y, Wang J, Abula S, Zhang J, Qin T, Chen X, Chen X, Khakame SK, Dang BK.
(Source-Institute of Traditional Chinese Veterinary Medicine, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing 210095, PR China.)
Abstract
Total Auricularia auricula polysaccharide (AAP(t)) was prepared by extracting and removing the proteins. Column chromatography was used to further graded it into AAP(1) and AAP(2). Three AAPs were modified by chlorosulfonic acid-pyridine method to obtain three sulfated AAPs (sAAPs), sAAP(t), sAAP(1) and sAAP(2), respectively. Three sAAPs and Newcastle disease virus (NDV) were added into cultivation system of chicken embryo fibroblast (CEF) in three manners, pre-, post- and simultaneous-adding polysaccharide with NDV respectively, taking three non-modified AAPs as control. Their anti-viral activities were compared by MTT method. The results showed that sAAPs and AAPs at a certain concentration could significantly inhibit the cellular infectivity of NDV in three manners. The effects of sAAPs were better than that of AAPs. It indicated that sulfated modification could enhance the antiviral activity of AAP. sAAP(1) and sAAP(t) possessed stronger activity and would be as the component of a new-type antiviral drug.
Black fungus Powder Extract and hypolipidemic
>Chemical properties of a polysaccharide purified from solid-state fermentation of auricularia auricular and its biological activity as a hypolipidemic agent.
(Source-College of Food Science, Fujian Agriculture and Forestry Univ. Fuzhou, Fujian 350002, China; Natl. Engineering Research Center of Juncao, Fuzhou, Fujian 350002, China.)
Abstract
A water-soluble crude polysaccharide was extracted by hot water from Auricularia auricular mycelium grown under solid-state fermentation (SSF). The crude polysaccharide was purified by DEAE Sephadex A-50 and Sephadex G-200 chromatography. Fourier transform infrared spectroscopy and nuclear magnetic resonance ((1) H NMR) spectroscopy were used to investigate the structure of the purified A. auricular polysaccharide (AAP-I) and revealed that it is α-glycosidically linked. After 14 and 28 days of AAP-I orally administered, the AAP-I significantly decreased the levels of total cholesterol, triglyceride, and low-density lipoprotein cholesterol in mice in which hyperlipidemia had been induced by a high fat diet (P < 0.05). The results revealed that AAP-I from SSF of A. auricular mycelium possesses potent hypolipidemic properties. The polysaccharide may be useful as a functional food additive and a hypolipidemic agent.
Black fungus Powder Extract and against tumor cells
Comparative antitumor activity of jelly ear culinary-medicinal mushroom, Auricularia auricula-judae (Bull.) J. Schrot. (higher basidiomycetes) extracts against tumor cells in vitro.
(Source-Laboratory of Veterinary Pharmacology, College of Veterinary Medicine, Kyungpook National University, Daegu 702701, Republic of Korea.)
Abstract
The present study compares the antitumor activity of extracts from Auricularia auricula-judae, Phellinus gilvus, Ganoderma lucidum, and 100 Korean wild plants in the P388D1 macrophage cell line. The antitumor activity of A. auricula-judae extract (44.21%) did not differ significantly (P < 0.05) from those of Ph. Gilvus (39.46%) and G. lucidum (36.64%) at 1 mg/mL of concentration. Among 100 wild plants, Morus bombycis f. kase, Draba nemorosa var. hebecarpa, Sedum oryzifolium, Lotus corniculatus var. japonicus, and Auricularia auricula-judae 70% ethanol extracts inhibited the viability of tumor cells by 41.85%, 37.31%, 30.29%, 31.98%, and 25.40% at 3 mg/mL of concentration, while inhibition concentration (IC50) values were 1.81, 1.49, 1.05, 1.10, and 0.72 mg/mL, respectively. In Sarcoma 180, NCI H358, and SNU 1 cell lines, the inhibitory activities of A. auricula-judae extract were 65.71%, 69.76%, and 68.01%, respectively. Taken together, the results obtained from the present study indicated that four plant extracts (4% of tested wild plants) and A. auricula-judae extract with similar levels of Ph. Gilvus and G. lucidum extracts may be new potential antitumor agents.
- Main Benefits
Antioxidant, anticancer, antiviral activity, anti-hypolipidemic
Applications & Uses
- Markets
- Food & Nutrition Applications
- Dosage
Many Black fungus Powder Extract supplements recommend a dosage of around 1500 mg to 2000 mg.
- Applications
Medicine, food additive, dietary supplement, sports nutrition
Properties
- Appearance
- Brown Fine Powder
- Specifications
| Value | Units | Test Method / Conditions | |
| Polysaccharides | 10 - 30 | % | — |