Pfanstiehl

Pfanstiehl Arginine A-170 is a L-Arginine, High Purity / Low Endotoxin-Low Metals, USP/EP/JP/ChP.

Pfanstiehl Galactose G-126-2 is a D-Galactose, Plant-Derived, High Purity Low Endotoxin.

Pfanstiehl Dextrose D-112 is known as dextrose USP (Anhydrous).

Pfanstiehl Mannose M-164-1 is a C-2 epimer of glucose and a sugar monomer of the aldohexose series of carbohydrates. Mannose is important in human metabolism, particularly in the proper glycosylation of native proteins. It follows that extracellular mannose has been demonstrated to play a critical and ever-increasing role in the optimization of protein therapeutics bioproduction. Pfanstiehl Brand High Purity Low Endotoxin Mannose was developed specifically for biopharmaceutical use, to the highest quality and purity standards. It has been utilized as a key component to ensure consistency of therapeutic glycosylation, potency, and yield. Mannose M-164-1 is a high purity (Low Endotoxin).

Pfanstiehl Mannitol M-109-7 is classified as a sugar alcohol and is derived from a sugar (mannose) by reduction. Other widely known polyols are xylitol and sorbitol. Mannitol and sorbitol are isomers, differing only in the orientation of the hydroxyl group on carbon two. The physical properties of mannitol make it suitable for use as a bulking agent in tableting. However, it also has unique chemical properties that enable it to stabilize a wide variety of pharmaceutical preparations, including liquid formulations, as well as protect proteins from denaturation/degradation upon lyophilization, spray drying, and reconstitution. Pfanstiehl Brand High Purity Low Endotoxin Mannitol was developed specifically for biopharmaceutical use, to the highest quality and purity standards. It has been utilized as a key component to stabilize proteins during formulation, freeze drying, and finish/fill applications.

Pfanstiehl Maltose M-132-1 is a disaccharide consisting of two glucose molecules with an α-1,4 glucosidic bond. Upon injection, it is only requires a minimal amount of insulin, having little impact influence on blood-sugar levels. Hence, it is commonly used to stabilize intravenous IG infusions, among other protein-based formulations. Pfanstiehl Brand, High Purity Low Endotoxin Maltose is a high quality, pharmaceutical grade maltose that can be used in bioprocessing and parenteral applications. In addition to use in nutritional intravenous fluids in certain countries, it can be also used as an excipient for protein stabilization.

Pfanstiehl Trehalose T-104-4 is a non-reducing disaccharide consisting of two glucose molecules linked by an α, α–1,1 bond. Pfanstiehl Brand, High Purity Low Endotoxin Trehalose is used in the biopharmaceutical industry to stabilize proteins, lipids, and carbohydrates throughout the formulation and freeze/thaw life cycle of therapeutics. It is also widely applied as a key component in cryopreservation/freeze media to stabilize cell membranes and improve the recovery and robustness of cells used for bioproduction and cell therapy.

Pfanstiehl Sucrose S-124-1-MC is a non-reducing crystalline disaccharide made up of glucose and fructose, found in many plants but extracted as ordinary sugar mainly from sugar cane and sugar beets. Pfanstiehl Brand, High Purity Low Endotoxin Sucrose is used in the biopharmaceutical industry to stabilize proteins, lipids, and carbohydrates throughout the formulation and freeze/thaw life cycle of therapeutics. It is also widely applied as a cryopreservative and media supplement in a variety of cell-based bioprocesses. It is preferred to trehalose in applications where solubility and/or viscosity issues are paramount.