Knowde Enhanced TDS
Identification & Functionality
- Ingredient Name
- Food Ingredients Functions
- Pharma & Nutraceuticals Functions
Features & Benefits
- Benefit Claims (Health)
- Product Background
- Cancer, HIV/AIDS, and depression are major 21st-century diseases affecting 3% of the global population.
- Chronic insomnia in Taiwan is prevalent at 10.7%, leading to societal and economic burdens.
- Conventional sleep aids with side effects and dependencies have paved the way for natural and safe sleep-promoting probiotics in the healthcare market.
- The gut microbiota, with over 100 trillion microbes, plays a vital role in immune regulation and gut-brain communication.
- Probiotics in the gut interact with the central nervous system, producing around 80% of the "happy hormone" serotonin.
- This serotonin, stimulated by probiotic fermentation, relieves stress and promotes sleep through signals to the brain via the vagus nerve.
- Product Benefits
- Research center introduces sleep-promoting probiotics that excel in producing γ-aminobutyric acid (GABA), a sleep-inducing factor.
- The strain combination SA0301 includes Lactobacillus plantarum LPL28, Lactobacillus acidophilus TYCA06, and Bifidobacterium breve CCFM1025, known for their sleep and stress-relief benefits.
- These strains stimulate serotonin secretion in the gut, transmitting happiness signals to the brain via the vagus nerve. A patent application is underway for this formulation.
- Bifidobacterium breve CCFM1025 has demonstrated promising results in animal models, elevating short-chain fatty acids (SCFAs) and tryptophan levels, alleviating depression and anxiety symptoms, and altering gut microbiota.
- Clinical studies on Major Depressive Disorder (MDD) patients revealed improved gut microbiota and tryptophan metabolism, leading to enhanced mood and better sleep.
- Incorporate these sleep-promoting probiotics into your routine to support a healthy gut-brain connection, promote better sleep quality, and boost emotional well-being.
Applications & Uses
- Markets
Properties
- Typical Properties
| Value | Units | Test Method / Conditions | |
| Viable Microorganisms Count | 1000 | billion CFU/g | — |