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Pharm-Rx Aprepitant

Chemical Name: Aprepitant

CAS Number: 170729-80-3

    Knowde Enhanced TDS

    Identification & Functionality

    Chemical Name
    Molecular formula
    C₂₃H₂₁F₇N₄O₃
    Definition

    Aprepitant contains NLT 98.0% and NMT 102.0% of aprepitant (C₂₃H₂₁F₇N₄O₃), calculated on the anhydrous and solvent-free basis.

    Chemical Structure

     - 1

    Applications & Uses

    Properties

    Typical Properties
    ValueUnitsTest Method / Conditions
    Molecular Weight534.43

    Regulatory & Compliance

    USP Reference Standards
    • USP Aprepitant RS
    • USP Aprepitant Related Compound B RS
    • S,R, S-Enantiomer: 3-[[(25, 3R)-2-[(5)-1-[3,5-
    • Bis(trifluoromethyl)phenyl|ethoxy]-3-(4-fluorophenyl) morpholino]methyl]-1 H-1,2,4-triazol-5(4H)-one. C23H21F,N,03 534.43
    • USP Desfluoro Aprepitant RS
    • 5-[[(2R, 35)-2-[(R)-1-[3,5-Bis(trifluoromethyl)phenyl] ethoxy]-3-pheny|morpholino]methyl]-2H-1,2,4-triazol- 3(4H)-one. C23H22F6N403 516.44

    Storage & Handling

    Storage Information

    Preserve in well-closed containers, protected from light. Store at room temperature.