Pharm-Rx Bupropion HCL

Identification & Functionality

Chemical Name

Bupropion Hydrochloride

Molecular formula

C₁₃H₁₈ClNO · HCl

Technologies

Pharmaceuticals & Nutraceuticals

Product Families

Pharmaceuticals & Nutraceuticals — Pharmaceutical Actives & Precursors

Active Pharmaceutical Ingredients (APIs)

Definition

Bupropion Hydrochloride contains not less than 98.0% and not more than 102.0% of bupropion hydrochloride (C₁₃H₁₈ClNO · HCl), calculated on the anhydrous basis.

Chemical Structure

Properties

Typical Properties

	Value	Units	Test Method / Conditions
Molecular Weight	276.2	—	—

Regulatory & Compliance

USP Reference Standards

• USP Bupropion Hydrochloride RS
• USP Bupropion Related Compound A RS
• [NOTE—May also be labeled as USP Bupropion Hydrochloride Related Compound A RS.] 2-(tert-Butylamino)-1-(4-chlorophenyl)propan-1-one hydrochloride; Also known as
• (USP 1-Aug-2021) 2-(tert-Butylamino)-4′-chloropropiophenone hydrochloride. C₁₃H₁₈ClNO · HCl 276.21
• USP Bupropion Related Compound B RS
• [NOTE—May also be labeled as USP Bupropion Hydrochloride Related Compound B RS.] 2-(tert-Butylamino)-1-(3-bromophenyl)propan-1-one hydrochloride; Also known as
• (USP 1-Aug-2021) 2-(tert-Butylamino)-3′-bromopropiophenone hydrochloride. C₁₃H₁₈BrNO · HCl 320.66
• USP Bupropion Related Compound C RS
• [NOTE—May also be labeled as USP Bupropion Hydrochloride Related Compound C RS
• (USP 1-Aug-2021)] 1-(3-Chlorophenyl)-2-hydroxypropan-1-one. C₉H₉ClO₂  (USP 1-Aug-2021) 184.62
• (USP 1-Aug-2021)
• USP 3-Chlorobenzoic Acid RS
• 3-Chlorobenzoic acid. C₇H₅ClO₂ 156.57

Storage & Handling

Storage Information

Preserve in well-closed, light-resistant containers. Store at room temperature.