Pharm-Rx Erythromycin Thiocyanate

Identification & Functionality

Chemical Name

Erythromycin thiocyanate

Molecular formula

C₃₇H₆₇NO₁₃

Technologies

Pharmaceuticals & Nutraceuticals

Product Families

Pharmaceuticals & Nutraceuticals — Pharmaceutical Actives & Precursors

Active Pharmaceutical Ingredients (APIs)

Definition

Erythromycin consists primarily of erythromycin A (C₃₇H₆₇NO₁₃). The sum of the percentages of erythromycin A, erythromycin B, and erythromycin C is NLT 85.0% and NMT 100.5%, calculated on the anhydrous basis.

Chemical Structure

Properties

Typical Properties

	Value	Units	Test Method / Conditions
Molecular Weight	733.94	-	-

Regulatory & Compliance

USP Reference Standards

• USP Erythromycin RS
• USP Erythromycin B RS
• 12-Deoxyerythromycin; (3R,4S,5S,6R,7R,9R,11R,12S,13R,14R)-6-{[(2S,3R,4S,6R)-4-(Dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-14-ethyl-7,12-dihydroxy-4 {[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione. C₃₇H₆₇NO₁₂ 717.94 (USP 1-Dec-2019)
• USP Erythromycin C RS
• 3′′-O-Demethylerythromycin; (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-4-{[(2R,4R,5S,6S)-4,5-Dihydroxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-6-{[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]oxy}-14-ethyl-7,12,13-trihydroxy-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione. C₃₆H₆₅NO₁₃ 719.91 (USP 1-Dec-2019)
• USP Erythromycin Related Compound N RS N-Demethylerythromycin A; (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-14-Ethyl-7,12,13-trihydroxy-4-{[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl]oxy}-6-{[(2S,3R,4S,6R)-3-hydroxy-6-methyl-4-(methylamino) tetrahydro-2H-pyran-2-yl]oxy}-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-

Storage & Handling

Storage Information

Preserve in tight containers.