Pharm-Rx Irinotecan HCL

Identification & Functionality

Chemical Name

Irinotecan Hydrochloride Hydrate

Molecular formula

C₃₃H₃₈N₄O₆· HCl · 3H₂O

Technologies

Pharmaceuticals & Nutraceuticals

Product Families

Pharmaceuticals & Nutraceuticals — Pharmaceutical Actives & Precursors

Active Pharmaceutical Ingredients (APIs)

Chemical Structure

 

Definition

Irinotecan Hydrochloride contains NLT 98.0% and NMT 102.0% of C33H38N4O6 · HCl, calculated on the anhydrous basis.

Applications & Uses

Markets

Healthcare & Pharma

Applications

Healthcare & Pharma — Drug Delivery & Care Solutions

Other Drug & Care Solutions

Properties

Typical Properties

	Value	Units	Test Method / Conditions
Molecular Weight	623.14	—	—

Regulatory & Compliance

USP Reference Standards

USP Irinotecan Hydrochloride RS
USP Irinotecan Related Compound A RS (S)-4-Ethyl-4,9-dihydroxy-1H-pyrano[3’,4’:6,7] indolizino[1,2-b]quinoline-3,14(4H,12H)-dione.
C₂₀H₁₆N₂O₅  364.35

USP Irinotecan Related Compound B RS (S)-4,11-Diethyl-4,9-dihydroxy-1H-pyrano[3’,4’:6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione.
C₂₂H₂₀N₂O₅  392.40

USP Irinotecan Related Compound C RS 11-Ethyl-4-hydroxy-4-methyl-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3′,4′:6,7]indolizino[1,2-b]quinolin-9-yl (1,4′-bipiperidine)-1′carboxylate
hydrochloride.
C₃₂H₃₆N₄O₆· HCl  609.11

USP Irinotecan Related Compound D RS (R)-9-[(1,4’-Bipiperidine)-1’-carbonyloxy]-4,11-diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano[3’,4’:6,7]indolizino[1,2-b]quinoline hydrochloride, trihydrate.
C₃₃H₃₈N₄O₆· HCl · 3 H₂O  677.18

Storage & Handling

Storage Information

Preserve in tight, light-resistant containers, and store at controlled room temperature.