Pharm Rx - 34552-83-5

Knowde Enhanced TDS

Identification & Functionality

Chemical Name: Loperamide Hydrochloride
Molecular formula: C₂₉H₃₃ClN₂O₂ · HCl
Technologies: Pharmaceuticals & Nutraceuticals
Product Families: Pharmaceuticals & Nutraceuticals — Pharmaceutical Actives & Precursors
Active Pharmaceutical Ingredients (APIs)
Definition: Loperamide Hydrochloride contains not less than 98.0% and not more than 102.0% of loperamide hydrochloride (C₂₉H₃₃ClN₂O₂ · HCl), calculated on the dried basis.
Chemical Structure

Applications & Uses

Markets: Healthcare & Pharma
Applications: Healthcare & Pharma — Drug Delivery & Care Solutions
Other Drug & Care Solutions

Regulatory & Compliance

USP Reference Standards: USP Loperamide Hydrochloride RS USP Loperamide System Suitability Mixture RS The mixture contains loperamide hydrochloride and the following impurities (other impurities may also be present): Chlorophenylpiperidinol; 4-(4-Chlorophenyl)piperidin-4-ol

C11H14ClNO 211.69 Deschloroloperamide; 4-(4-Hydroxy-4-phenylpiperidin-1-yl)-N,N-dimethyl-2,2- diphenylbutanamide

C29H34N2O2 442.59 Loperamide trans-N-oxide; (1r,4s)-4-(4-Chlorophenyl)-1-[4-(dimethylamino)-4-oxo- 3,3-diphenylbutyl]-4-hydroxypiperidine 1-oxide

C29H33ClN2O3 493.04 Loperamide cis-N-oxide; (1s,4r)-4-(4-Chlorophenyl)-1-[4-(dimethylamino)-4-oxo- 3,3-diphenylbutyl]-4-hydroxypiperidine 1-oxide

C29H33ClN2O3 493.04 Anhydroloperamide; 4-[4-(4-Chlorophenyl)-5,6-dihydropyridin-1(2H)-yl]-N,N- dimethyl-2,2-diphenylbutanamide

C29H31ClN2O 459.02 Loperamide piperidinolamide; 1,4-Bis[4-(4-chlorophenyl)-4-hydroxypiperidin-1-yl]-2,2- diphenylbutan-1-one

C38H40Cl2N2O3 643.64 Loperamide biphenyl analog; 4-[4-(4′-Chlorobiphenyl-4-yl)-4-hydroxypiperidin-1-yl]- N,N-dimethyl-2,2-diphenylbutanamide

C35H37ClN2O2 553.13 Loperamide quaternary salt; 4-(4-Chlorophenyl)-1,1-bis[4-(dimethylamino)-4-oxo- 3,3-diphenylbutyl]-4-hydroxypiperidin-1-ium chloride

C47H53Cl2N3O3 778.85 (USP 1-May-2020)

Storage & Handling