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Pharm-Rx Spironolactone USP

Chemical Name: Spironolactone

CAS Number: 52-01-7

Certifications & Compliance: United States Pharmacopeia (USP)

    Knowde Enhanced TDS

    Identification & Functionality

    Chemical Name
    Molecular formula
    C₂₄H₃₂O₄S
    Chemical Structure

    Pharm-Rx Sodium Picosulfate USP - Chemical Structure - 1

    Defination

    Spironolactone contains NLT 97.0% and NMT 103.0% of spironolactone (C₂₄H₃₂O₄S), calculated on the dried basis.

    Applications & Uses

    Properties

    Typical Properties
    ValueUnitsTest Method / Conditions
    Molecular Weight416.57

    Regulatory & Compliance

    Certifications & Compliance
    USP Reference Standards
    • USP Spironolactone RS
    • USP Spironolactone Related Compound A RS
    • 2′R)-3′,4′-Dihydro-5′H-spiro[androst-4,6-diene-17,2′- furan]-3,5′-dione. C₂₂H₂₈O₃ 340.46 USP Spironolactone Related Compound B RS
    • 2′R)-7α-(Acetylthio)-5′H-spiro[androst-4-ene-17,2′- furan]-3,5′-dione. C₂₄H₃₀O₄S 414.56
    • USP Spironolactone Related Compound C RS (2′R)-3′,4′-Dihydro-5′H-spiro[androst-4-ene-17,2′-furan]- 3,5′-dione. C₂₂H₃₀O₃ 342.47
    • USP Spironolactone Related Compound D RS (2′R)-7α-(Acetyldisulfanyl)-3′,4′-dihydro-5′Hspiro[ androst-4-ene-17,2′-furan]-3,5′-dione. C₂₄H₃₂O₄S₂ 448.64
    • USP Spironolactone Epimer Mixture RS
    • USP Spironolactone Related Compound C RS (2′RIt contains a mixture of approximately 39% of spironolactone and 56% of 7-epispironolactone: (2′R)-7β-(Acetylthio)-3′,4′-dihydro-5′H-spiro[androst-4- ene-17,2′-furan]-3,5′-dione. C24H32O4S 416.57)-3′,4′-Dihydro-5′H-spiro[androst-4-ene-17,2′-furan]- 3,5′-dione. C₂₂H₃₀O₃ 342.47
    • USP Spironolactone Related Compound I RS
    • S-[17α-(Ethoxymethyl)-17-hydroxy-3-oxoandrost-4-en- 7α-yl]ethanethioate. C₂₄H₃₆O₄S 420.61

    Storage & Handling

    Storage Information

    Preserve in well-closed containers.