Knowde Enhanced TDS
Identification & Functionality
- Carrier
- Chemical Name
- CASE Ingredients Functions
- Fluids & Lubricants Functions
- CAS No.
- 2634-33-5
- EC No.
- 220-120-9
- Technologies
Features & Benefits
- CASE Ingredients Features
- Fluids & Lubricants Features
- Key Features
- Used as a preservative of aqueous and water miscible chemicals and technical products.
- Broad antimicrobial efficacy against bacteria, yeasts and fungi.
- Often effective where other preservatives fail, especially at critical temperature and pH-values.
- Free from formaldehyde, formaldehyde releasers, phenolics, heavy metals, halogens.
- Non-volatile
- Excellent thermal stability (-5° - 120°C)
- Excellent chemical stability.
- Excellent long term efficacy.
- Good compatibility with other raw materials.
- Product Highlights
PROMEX™ Na20S meets the highest purity requirements. Technically generated impurities are often the cause of undesired side effects in terms of toxicological or technical properties. These impurities are reduced to a minimum in PROMEX™ Na20S.
PROMEX™ Na20S penetrates the cells of microorganisms, reacts with vital parts of the cells and inactivates important substrates and enzymes necessary to normal cell function. These relatively unspecific reactions exhibit a bactericidal effect and minimize adaptation or the development of microbial resistance.- Microbial Deterioration
PROMEX™ Na20S prevents microbial deterioration of products and resulting consequences such as:
- Phase separation
- Odor build-up
- Gas build-up
- Changes in viscosity
- Build-up of health threatening toxins
Applications & Uses
- Applications
- Fluids & Lubricants Type
- Fluids & Lubricants End Use
- Applications
PROMEX™ Na20S is highly suitable for the preservation of a magnitude of aqueous formulations due to its good thermal and chemical stability. It shows highest efficacy in a wide pH range of pH 4 - 12 and is chemically stable from pH 2 - 12. Experience shows that compatibility with most products and raw materials is excellent, although compatibility testing is recommended for special formulations.
Application areas:- Paints
- Polymer emulsions
- Adhesives
- Metal working fluids
- Household cleaners
- Printing inks
- Starches
- Fount solutions
- Dispersions
Properties
- Soluble in
- Water
- Typical Properties
- Characteristic Properties
- Glycolic, yellowish solution
- Odorless at use levels
- Compatible with non-ionic and anionic surfactants
| Value | Units | Test Method / Conditions | |
| Density (20°C) | ca. 1.1 | kg/l | — |
| pH Value (0.1%) | ca. 9 - 10 | — | — |
Regulatory & Compliance
- Certifications & Compliance
- Chemical Inventories
- Regulatory Approvals (Na20S)
- USEPA Registration No. 80285-2 (as PROMEX™ 20S)
- CDPR (California) Registration No. 80285-2-AA
- Istituto Superiore di Sanità (ISS) (Italy) Company Code No. 3497368; Product Code AUT-1
- BAuA Reg.-Nr. PT 2 - N-32259; PT 6 - N-32258; PT 12 - N-31842
- Regulatory Approvals (BIT)
- Biocidal Products Directive (BPD) Notification No. N458.
- BfR Rec. XIV Preservative for polymer emulsions in food contact applications.
- BfR Rec. XXXVI Slimicide for manufacture of paper used in food contact applications.
- BAuA Reg. Nr. PT2 – N-32280; PT6 – N-32281
- USEPA Registration. No. 707-310-73930
- FDA 21 CFR 176.170 Components of paper and paperboard in contact with fatty and aqueous foods (for use as a preservative in paper coating compositions and limited to use at a level not to exceed 0.01 mg/ln\2 finished paper and paperboard.
- FDA 21 CFR 176.180 Components of paper and paperboard in contact with dry food (for use as a preservative in paper coating compositions and limited to use at a level not to exceed 0.02 mg/ln\2 finished paper and paperboard.
- FDA 21 CFR 176.300 Slimicide for manufacture of paper used in food contact applications (for use at a level of 0.06 lb per ton of dry weight fiber.
- FDA 21 CFR 177.2600(c)(4)(ix) Rubber articles intended for repeated use (for use as a biocide in uncured liquid rubber latex not to exceed 0.02 percent by weight of the latex solids, where the total of all items listed in paragraph (c)(4)(ix) of this section does not exceed 5 percent of the rubber product).
- FDA 40 CFR 180.920 (formerly FDA 40 CFR 180.1001(d)) Ingredients in pesticide formulations (exempted from the requirement of a tolerance when used in accordance with good agricultural practice as inert (or occasionally active) ingredients in pesticide formulations applied to growing crops only. As a preservative (not more than 0.1% of formulation. Not more than 0.02 lb to be applied per acre).
- CEPA (Canadian Environmental Protection Act): All ingredients are on the DSL.
Technical Details & Test Data
- Microbial Efficacy
Bacteria Mic (ppm) Fungi and yeasts Mic (ppm) Pseudomonas aeruginosa 250 Aspergillus niger 350 Pseudomonas putida 250 Chaetomium globosum 400 Enterobacter cloacae 40 Penicillium notatum 125 Escherichia coli 80 Saccharomyces cerevisiae 250 Staphylococcus aureus 40 Rhodotorola rubra 500 Streptococcus lactis 15 Candida albicans 100 Streptococcus faecalis 40 Endomycopsis albicans 250 - Ecological Effects
Biodegradable. Permanent dosing with 10 ppm a.i. shows no negative effect on aerobic oxidation with activated sludge. For anaerobic degradation this level is 2 ppm. BIT has low bioaccumulation potential: Log P oct/w = 1.11 .
- Aquatic Toxicity (BIT)
LC50 96h, Rainbow Trout 1.3 mg/l EC50 48h, Daphnia 1.5 mg/l EC50 96h, Algae 0.084 mg/l - Toxicological Effects (BIT)
LD50, oral, rat 1193 mg / kg body weight (active ingredient)
LD50, dermal, rat >4115 mg / kg body weight (active ingredient)
- Dermatological Effects (BIT)
Study Date Result Primary skin irritation 1996 moderately irritating Sensitization – Bühler 1997 not considered a sensitizer Sensitization – MagnussonKligman 1998 9 / 20 animals reacted positively to 10 % w/v in ethanol.
BIT is considered a moderate sensitizer under the
conditions of the studyLong term studies in humans showed low allergy rates:
Conc. N tested ? / irritant N positive % positive RI BIT 0.10 % Pet. 1191 5 14 1.2 0.5 The reaction-index (RI) gives the ratio of questionable or irritant reactions to proven allergic reactions. Cross reactions to other isothiazolinones are considered very rare. Above 500 ppm active ingredient BIT can cause sensitization.