Purewhite™ - Radiant

Knowde Enhanced TDS

Identification & Functionality

Carrier: Aqua,
Butylene Glycol
INCI Name: Morus Alba Root Extract
Cosmetic Ingredients Functions: Brightening Agent,
Lightening Agent,
Whitening Agent
Main Ingredient: Mulberroside A
CAS No.: 94167-05-2
EC No.: 303-403-2
Technologies: Cosmetic Ingredients
Product Families: Cosmetic Ingredients — Cosmetic Actives
Skin Actives
Preservative: Non-added
Chemical Structure

Features & Benefits

Benefit Claims: Brightening,
Dark Circles Reduction,
Lightening Effect,
Shine & Radiance,
Skin Whitening
Labeling Claims: Clean at Sephora,
Preservative-free,
Ulta Beauty's Conscious Beauty
Features: Mulberries have been adapted to a very wide variety of local conditions in the world. Korea has about 40 different Types. Not all types of the tree contain have not the mulberroside A but some types have rich of the active ingredient. Its depends on the region where they grow as well as the climate and the soil.

Applications & Uses

Application Format: Creams,
Essence,
Gel,
Leave On,
Lotions,
Masks,
Rinse Off
Skin Care Applications: Facial Mask,
Massage Products
Applications: Cosmetics; skin, lotion, cream, mask pack, essence, massage cream, eye cream, etc
Dosage: 0.5-2%

Properties

Technical Details & Test Data

Proposed intracellular signaling pathways for the whitening effect action of Purewhite ™ in melanocyte
Main Biological Effects for Cosmetics: Tyrosinase & Melanogenesis inhibition activity

Concentration (%) Inhibition effect (% of control) IC50 (%)

Tyrosinase inhibition activitiy
0.005 53.0 + 2.6
0.00397

0.01 75.0 + 0.2

0.02 84.0 + 1.3

Melanogenesis inhibition activity
0.005 8.83 + 2.3
0.0184

0.01 21.3 + 4.3

0.02 56.4 + 1.4

Morus alba extract shows dose-dependent inhibitory effects on mushroom tyrosinase activity and melanin production. Also we identified Morus alba extract has not cytotoxicity in these range concentration between 0.005-0.02%.

• Whitening effect (In vivo test)

PurewhiteTM have a promising potential for use as an effective skin-whitening agent more than arbutin

Packaging & Availability

Storage & Handling

	Concentration (%)	Inhibition effect (% of control)	IC50 (%)
Tyrosinase inhibition activitiy	0.005	53.0 + 2.6	0.00397
	0.01	75.0 + 0.2
	0.02	84.0 + 1.3
Melanogenesis inhibition activity	0.005	8.83 + 2.3	0.0184
	0.01	21.3 + 4.3
	0.02	56.4 + 1.4