Knowde Enhanced TDS
Identification & Functionality
- INCI Name
- Cosmetic Ingredients Functions
- CAS No.
- 1197-18-8
- EC No.
- 214-818-2
- Technologies
- Product Families
Features & Benefits
- Benefit Claims
- Functions
Whitening and prevent pigmentation
- Reduce or remove the pigmentation of skin
- Prevent and/or treat pigmentations such as chloasmas, freckles, sunburn, dark skin and melanoderma caused by a drug such as steroid
- Minimize dark spot area due to sun exposure.
- Anti-inflammation
- Act on the chronic mild inflammatory condition at the sites of spots, to suppress melanocyte activation
Inhibit or improve skin roughness
Restore damaged skin caused by UVA/UVB, pollution or other environmental factors.
Mechanism of whitening skin:- Block melanin formation path induced by ultraviolet rays
- Prevent melanin accumulation
- Decreases melanocyte tyrosinase activity by preventing the binding of plasminogen to the keratinocytes, which results in reduction of prostaglandins and arachidonic acid, which are inflammatory mediators involved in melanogenesis.
Synergistic effects with other whitening ingredients:
Tranexamic acid produces good synergistic effect when combined with ascorbic acid or its derivatives such as magnesium ascorbyl phosphate, 3-O-ethyl ascorbic acid, disodium adenosine triphophate, escinol (deacylated product of escin under hydrolysis by sodium methylate), L-cysteine. Penetration enhancers helps the transdermic absorption of tranexamic acid into spots.
Applications & Uses
- Markets
- Applications
- Application Format
- Skin Care Applications
- Sun Care Applications
- Applications and Uses
Applications
Tranexamic acid is suitable to all kinds of skin for removing pigmentation, whitening skin and reducing spots, such as:
- Pigmentation after sun exposure
- Dark spots
- Sensitive skin
- Acne and inflammation
- Postoperative care after laser, pulsed light treatment
Use Level: 0.5% ( cosmetics); cosmaceuticals: 2.0-3.0%
Properties
- Odor
- Odorless
- Appearance
- White crystalline powder
- Soluble in
- Water, Glacial acetic acid
- Insoluble in
- Alcohol, Acetone
- Typical Properties
| Value | Units | Test Method / Conditions | |
| Arsenic Content | max. 2 | mg/kg | - |
| Cadmium Content | max. 5 | mg/kg | - |
| Lead Content | max. 5 | mg/kg | - |
| Loss on Drying | max. 0.5 | % | - |
| Mercury Content | max. 1 | mg/kg | - |
| pH Value | 7.0 - 8.0 | - | - |
| Purity | min. 99 | % | HPLC |
| Residue on Ignition | max. 0.1 | % | - |
Regulatory & Compliance
- Certifications & Compliance
- Quality System
Manufacture according to quality system registered to ISO 9001:2008
Technical Details & Test Data
- Efficacy and Safety Comparison of Tranexamic Acid with Other Whitening Ingredients
Tranexamic acid is relatively stable to light, temperature, pH, and oxygen, and no special protections are required to maintain its whitening effect, as compared with conventional whitening ingredients. It is no irritant and no sensitive to skin and is safe for use in whitening cosmetics.
Azelaic acid L- ascorbic acid Arbutin Tranexaminc acid Reduction
of melanin
Inhibit√ √ √ Tyrosinase √ √ √ No irritation √ Hypoallergenic √ Anti-
Inflammatory√ √
Packaging & Availability
Storage & Handling
- Shelf Life
- 2 Years
- Storage Information
- Store in room temperature and dry place, keep away from strong light heat.