CHLORHEXIDINE HCL - RN LABORATORIES - 3697-42-5

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Identification & Functionality

INCI Name: Chlorhexidine Dihydrochloride
Cosmetic Ingredients Functions: Anti-Septic,
Preservative
Molecular formula: C₂₂H₃₀Cl₂N₁₀.2HCl
EC No.: 223-026-6
CAS No.: 3697-42-5
Technologies: Cosmetic Ingredients
Product Families: Cosmetic Ingredients — Functionals
Antioxidants & Preservatives
Structure

Features & Benefits

Benefit Claims: Anti-Bacterial,
Anti-Infectious,
Antiseptic,
Effective Germ Control,
High Quality,
Preservation
Labeling Claims: Ulta Beauty's Conscious Beauty
Product Highlights: Chlorhexidine dihydrochloride is an effective antiseptic, disinfectant and preservative against a wide variety of gram-negative and gram-positive organisms. Bacteriostatic and bactericidal activity due to outer bacterial membrane disruption.

Directly inhibits Matrix metalloproteinases MMP-2, MMP-8, and MMP-9 possibly via a cation-chelating mechanism. Chlorhexidine Dihydrochloride improves the patient’s condition by performing the following functions: Destroying the cell membrane and killing the bacterial cell.

Chlorhexidine hcl is an high quality antiseptic, disinfectant and preservative, matching the highest quality standards with specifications as per your requirements.

Antiseptic; Matrix metalloproteinase inhibitor.
Definitions: Antiseptics (Anti-Infective Agents, Local) - Substances used on humans and animals that destroy harmful microorganisms or inhibit their activity.

Disinfectants - Substances used on inanimate objects that destroy harmful microorganisms or inhibit their activity. Disinfectants are classed as complete, destroying SPORES as well as vegetative forms of microorganisms, or incomplete, destroying only vegetative forms of the organisms.

Applications & Uses

Markets: Personal Care
Applications: Personal Care — Beauty & Care
Skin Care,
Treatment Products
Application Format: Creams,
Gel,
Leave On,
Ointments
Skin Care Applications: Body Cream,
Skin Gel
Treatment Product Applications: Ointments
Uses: Chlorhexidine hcl is a high quality antiseptic, disinfectant and preservative used in a broad field of indications.

Antiseptic - Chlorhexidine hydrochloride is used typically in combination with other API’s as soar throat tablets

Disinfectant -Chlorhexidine hydrochloride is used as disinfectant for peripherally inserted central catheters (PICC’s) or central venous catheters (CVC’s)

Preservative -In the cosmetic field Chlorhexidine hydrochloride is used as a preservative in creams, ointments and gels.

Properties

Physical Form: Powder
Appearance: White or almost white crystalline powder
Typical Properties
Solubility: Sparingly soluble in water and propylene glycol, very slightly soluble in Ethanol 96%.

Regulatory & Compliance

Certifications & Compliance: GMP
Specification At Release: EP/USP as per requirement.
Regulatory Status: Chlorhexidine hcl matches the high quality regulatory standards of the european pharmaceutical and cosmetic industry.

API (Ph. Eur.)

GMP (Good Manufacturing Practice)

DMF (Drug Master File) issued 2011 No.25070

Cosmetic

Chlorhexidine dihydrochloride is registered in the CosIng (Cosmetic Ingredient Database).

This means that it can be used in cosmetics as a preservative with a maximum concentration of 0.3%.

Packaging & Availability

Storage & Handling

Stability: 36 months
Storage Conditions: Store at controlled temperature (15-30C)

Keep in the original drums tightly closed

Keep the drums away from direct sunlight