ROELMI HPC MeristeM - Oak Root Extract - Anti-Irritant

Knowde Enhanced TDS

Identification & Functionality

Carrier: Aqua
INCI Name: Oak Root Extract,
Pentylene Glycol,
Potassium Sorbate,
Sodium Benzoate
Cosmetic Ingredients Functions: Anti-Irritant,
Antioxidant,
Astringent,
Soothing Agent
Technologies: Cosmetic Ingredients
Product Families: Cosmetic Ingredients — Cosmetic Actives
Skin Actives
Cosmetic Ingredients — Functionals
Sensory Modifiers

Features & Benefits

Benefit Claims: Anti-Aging,
Anti-Inflammatory,
Antioxidant Properties,
Astringency,
Free Radical Scavenging,
Regenerating,
Skin Protection,
Soothing,
Stimulating,
Suitable for Sensitive Skin
Labeling Claims: Allergen-free,
Amine-free,
Animal Products-free,
BSE-free,
Chelate-free,
Ethanol-free,
Ethylene Oxide-free,
Formaldehyde-free,
GMO-free,
Glycol ether-free,
Nanomaterials-free,
Not Tested on Animals,
Phthalates-free,
Protein-free,
Stabilizers-free,
TSE-free,
Ulta Beauty's Conscious Beauty,
VOC-free,
Vegan
Product Highlights: Powerful Phenylpropanoids targeting protective & soothing anti-aging

Natural water extract from oak tree meristematic cells

Performing active to modulate post-acute stress pain

Improvement of skin wellness

Compatible with natural formulations

Available Saf-e-cacy® dossier on Safety & efficacy

Applications & Uses

Application Format: Leave On
Skin Care Applications: After Shaves
Use Level: 1.0%
Typical Applications: Protective & lenitive formulas

Anti-aging formulas

Irritated & damaged skin

Sensitive skins

Painful, thin or tired skins

Depilatories & after shave

Properties

Regulatory & Compliance

Chemical Inventories: AICS (Australia),
DSL (Canada),
EINECS (EU),
ENCS (Japan),
IECSC (China),
KECI (Korea),
NDSL (Canada),
NZIoC (New Zealand),
PICCS (Phillipines),
TSCA (USA)

Technical Details & Test Data

MeristeM: Designed to improve skin resistance to stress: Meristematic cells are rich in Phenylpropanoids (secondary plant metabolites responding to stresses such as wounding, UV and pollutants).
Their protective action through antioxidant and free
radical scavenging properties is due to their molecular structure as well as a strong chelating affinity for metals.
MeristeM principles are also able to inhibit the release of pain nervous mediator PGE2 through an antagonist action on TRPV3 nociceptive system, that open and allow
Ca2+ flow activating several signal pathways including cyclogenase leading to PGE2 release, responsible for skin acute nociception & hyperalgesia.
Regenerative intensive action to stimulate and activate skin tissues, MeristeM especially targets pain processes before or after stress, for the blooming of a relieved naturally beautiful skin.
In-vitro efficacy dossier: lenitive effect: Measure of the capacity to interact and modulate the main receptor of keratinocytes (TRPV3 channel), sensitive to heat and some kind of chemicals.

1% MeristeM inhibits the nociceptive system up to 54.7% in 24h.
Test Data: In-vitro test: diminution of TRPV3 nociceptive PEG2 release

In-vivo test: available on bibliography

Efficacy control: decrease of TRPV3 nociceptive activity (at every batch)

Storage & Handling

Shelf Life: 24 months
Storage: Keep the product in the original container well closed in fresh and dry place, repaired from humidity, light or heat sources.