Knowde Enhanced TDS
Identification & Functionality
- Active Component
- Chemical Family
- Chemical Name
- Ingredient Origin
- Cosmetic Ingredients Functions
- CAS No.
- 84775-66-6
- EC No.
- 283-895-2
- Technologies
- Product Families
- Product Details
- Product code : 0551
- Category : Intended for Cosmeceutical application
- Botanical/Scientific name : Glycyrrhiza glabra
- Plant part : Roots
- Preparation type : Extraction
- Solvent used for extraction : Acetone
- Solvent used in manufacture : Hexane and Ethyl alcohol
- Final extract ratio : 25:1 to 30:1
- Standardization : Glabridin
- Excipient used : None
Features & Benefits
- Labeling Claims
- Product Highlights
Licorice Extract is obtained from dried roots of Glycyrrhiza glabra and standardized for 4% Glabridin. Sabinsa also offers Licorice extract 40% Cetyl alcohol (CA) and Licorice extract 98%. This is a potential molecule, which is known for its skin lightening properties. Licorice possesses potent and effective anti-inflammatory, antioxidant as well as melanogenesis-inhibiting properties.
Applications & Uses
- Markets
- Applications
- Baby Care Applications
- Bath & Shower Applications
- Color Cosmetic Applications
- Hair Care Applications
- Skin Care Applications
- Sun Care Applications
- Treatment Product Applications
- Applications
- Skin Lightening
- Antioxidant
- Formulation Guidelines
- Use stainless steel (SS316) vessels for production. Avoid contact with iron or copper.
- Solubilize Licorice Extract in one of the recommended solvents before adding it to emulsion below 40°C
- Nonionicand anionic emulsifiers are to be used Maintain the pH of the formulation slightly acidic, preferably between pH 5.0-6.0
- Licorice Extract can be gelled using thickeners such as carbomer, acrylates copolymer and lecithin
- Opaque packaging is recommended for the finished product formulation
- Protect the finished product from exposure to direct heat and light
- Licorice Extract is suitable for use in creams and translucent to Opaque gels/ serums
- Licorice Extract is not suitable for use in clear gels/serums/ toners
- Use antioxidants and photostabilizers in the formulations
Properties
- Odor
- Characteristic odor
- Appearance
- Brown to brownish yellow powder
- Chemical Properties
- Physical Properties
- Typical Properties
- Other Properties
- Microbiological Values
| Value | Units | Test Method / Conditions | |
| Glabridin Content (HPLC - on dry basis) | 4.0 - 6.0 | % w/w | SLL/STP-G-002 |
| Value | Units | Test Method / Conditions | |
| Loose Bulk Density | 0.35 - 0.55 | g/ml | USP <616> |
| Sieve Test (Passes Through #20 Mesh) | min. 100 | % w/w | USP <786> |
| Loss on Drying (Dried at 105°C) | max. 5.0 | % w/w | USP <731> |
| Sieve Test (Passes Through #40 Mesh) | min. 85 | % w/w | USP <786> |
| Sieve Test (Passes Through #80 Mesh) | min. 70 | % w/w | USP <786> |
| Tapped Bulk Density | 0.40 - 0.80 | g/ml | USP <616> |
| Value | Units | Test Method / Conditions | |
| Alcohol Solubles (1% w/v solution in 95% v/v alcohol) | min. 90.0 | % w/w | SLL/STP-S-028 |
| Water Solubles (1% w/v solution in water) | max. 10.0 | % w/w | SLL/STP-S-028 |
| Value | Units | Test Method / Conditions | |
| Arsenic Content | max. 1 | ppm (μg/g) | USP <2232> |
| Cadmium Content | max. 1 | ppm (μg/g) | USP <2232> |
| Lead Content | max. 3 | ppm (μg/g) | USP <2232> |
| Mercury Content | max. 0.1 | ppm (μg/g) | USP <2232> |
| Value | Units | Test Method / Conditions | |
| Escherichia Coli | Negative | per 10g | USP <62> |
| Pseudomonas Aeruginosa | Negative | per 10g | USP <62> |
| Salmonella | Negative | per 10g | USP <62> |
| Staphylococcus Aureus | Negative | per 10g | USP <62> |
| Total Aerobic Microbial Count | max. 5000 | cfu/g | USP <61> |
| Total Yeasts and Molds Count | max. 100 | cfu/g | USP <61> |
Regulatory & Compliance
Technical Details & Test Data
- In Vitro Studies
Antioxidant Potential
Antioxidant strength of Licorice extract 40% CA was evaluated by both DPPH and ORAC assay.- Licorice extract 40% CA exhibited strong free radical scavenging activity when compared with the commonly used skin lightening agent, Kojic acid.
- ORAC activity of Licorice extract 40% CA was compared with other antioxidants. Results indicate that Licorice extract 40% CA provides higher antioxidant potential compared to Kojic acid.
Skin Lightening Potential
Licorice Extract 40% CA showed a strong tyrosinase and melanogenesis inhibitory activity when compared over kojic acid. It also exhibited strong antioxidant activity.Skin Lightening Potential Tyrosinase inhibition (ICso ug/ml) 0.25 Melanin inhibition (ICso ng/ml) 3 Antioxidant Potential DPPH inhibition (ICso pg/ml) 49 ORAC (mmol trolox equivalents/g) 3,256
Melanogenesis inhibition Activity
- Licorice extract 40% CA exhibited strong free radical scavenging activity when compared with the commonly used skin lightening agent, Kojic acid.
Packaging & Availability
- Regional Availability
Storage & Handling
- Shelf Life
- 5 Years
- Storage Condition
- Store at room temperature.