Sabinsa Cosmetics Sage Extract (Ursolic Acid 90%)

Identification & Functionality

Chemical Family: Plant Extracts
Chemical Name: Ursolic acid
INCI Name: Salvia Officinalis (Sage) Leaf Extract
Ingredient Origin: Natural Origin
Cosmetic Ingredients Functions: Anti-Aging Agent,
Anti-Inflammatory,
Thickener
CAS No.: 77-52-1
EC No.: 201-034-0
Technologies: Cosmetic Ingredients
Product Families: Cosmetic Ingredients — Functionals
Rheology Modifiers
Product Details: Product code : 1904

Category : Intended for Cosmeceutical application

Botanical/Scientific name : Salvia officinalis

Plant part : Leaves

Preparation type : Extraction

Solvent used for extraction : Toluene

Solvent used in manufacture : Methanol, Ethanol, Acetone, Ethyl acetate

Final extract ratio : 175:1 to 225:1

Standardization : Ursolic acid

Excipient used : None

Features & Benefits

Benefit Claims: Anti-Aging,
Anti-Inflammatory,
Anti-Irritant,
Collagen Boosting
Labeling Claims: BSE-free,
Clean at Sephora,
Credo Clean Standard,
GMO-free,
Natural,
Naturally Derived,
TSE-free,
Ulta Beauty's Conscious Beauty
Benefits: Ursolic Acid is found to have the following benefits:

Collagen and elastin synthesis

Repair photo-aged skin
Product Highlights: The genus name Salvia, is derived from the Latin salvere, "to be saved", in reference to the healing properties of plant. Ursolic acid forms the oilresistant barrier on the skin. It inhibits the action of elastase in the skin, thereby preventing the enzyme from attacking structural proteins. Ursolic acid has been used to treat photo-aged skin because it helps prevent and improve the appearance of wrinkles and age spots by restoring the skin's collagen bundle structures and its elasticity.

Applications & Uses

Suggested Use Level: 0.1 - 0.5 % w/w (Anti-aging)
Applications: Anti-inflammatory

Anti-aging

Collagen Build Up
Formulation Guidelines: Use stainless steel (SS316) vessels for production. Avoid contact with iron or copper

Solubilize Sage Extract in one of the recommended solvents before adding it to emulsion below 40°C

Nonionic and anionic emulsifiers are to be used

Maintain the pH of the formulation slightly acidic, preferably between pH 5.0-6.0

Sage Extract can be gelled using thickeners such as carbomer, acrylates copolymer and lecithin

Opaque packaging is recommended for the finished product formulation

Protect the finished product from exposure to direct heat and light

Sage Extract is suitable for use in creams and translucent to opaque gels/ serums

Sage Extract is not suitable for use in clear gels/serums/toners

Use antioxidants and photostabilizers in the formulations

Properties

Physical Form: Powder,
Solid
Appearance: Off white to creamish white powder
Insoluble in: Water
Physical Properties
Chemical Properties
Typical Properties
Other Properties
Microbiological Values
Solubility Data: Sage Extract Solubility Ratio

Dimethylethanolamine 1:5 at 50°C

Ethanol + DMEA (9:1) 1:10 at 50°C

N-Methyl-2-Pyrrolidone 1:13 at 50°C

	Value	Units	Test Method / Conditions
Ash Content	max. 1	% w/w	USP <561>
Sieve Test (Passes Through #20 Mesh)	min. 100	% w/w	USP <786>
Loss on Drying (Dried at 105°C)	max. 6.0	% w/w	USP <731>
Sieve Test (Passes Through #40 Mesh)	min. 80	% w/w	USP <786>
Sieve Test (Passes Through #80 Mesh)	min. 60	% w/w	USP <786>
Tapped Bulk Density	0.30 - 0.80	g/ml	USP <616>

	Value	Units	Test Method / Conditions
Ursolic Acid Content (HPLC - on dry basis)	90.0 - 101.0	% w/w	HPLC, SLL/STP-U-001

	Value	Units	Test Method / Conditions
Alcohol Solubles (1% w/v solution in 95% v/v alcohol)	min. 50.0	% w/w	SLL/STP-S-028

	Value	Units	Test Method / Conditions
Escherichia Coli	Negative	per 10g	USP <62>
Pseudomonas Aeruginosa	Negative	per 10g	USP <62>
Salmonella	Negative	per 10g	USP <62>
Staphylococcus Aureus	Negative	per 10g	USP <62>
Total Aerobic Microbial Count	max. 5000	cfu/g	USP <61>
Total Yeasts and Molds Count	max. 100	cfu/g	USP <61>

Technical Details & Test Data

In Vitro Studies: Anti inflammatory Potential
In house studies reveal that it effectively helps in maintaining skin structural components such as elastin, collagen and hyaluronic acid.

The functional properties of these components are as follows:

Elastin : For skin elasticity

Collagen : For skin firmness and density

Hyaluronic acid : For skin strength that keep skin supple and toned

It helps in preventing and reversing skin aging by inhibiting hyaluronidase, collagenase and elastase enzymes.

The comparative anti-inflammatory potential of Sage Extract (Ursolic 90%) and Sodium
Ursolate has been shown.

Storage & Handling

Knowde Enhanced TDS