Knowde Enhanced TDS
Identification & Functionality
- Chemical Family
- Chemical Name
- Ingredient Origin
- Cosmetic Ingredients Functions
- CAS No.
- 84082-79-1
- EC No.
- 282-025-9
- Technologies
- Product Families
- Product Details
- Product code : 1900
- Category : Intended for Cosmeceutical application
- Botanical/Scientific name : Salvia officinalis
- Plant part : Leaves
- Preparation type : Extraction
- Solvent used for extraction : Toluene
- Solvent used in manufacture : Methanol, Ethanol, Acetone, Ethyl acetate
- Final extract ratio : 75:1
- Standardization : Ursolic acid, Oleanolic acid
- Excipient used : None
Features & Benefits
- Labeling Claims
- Benefits
Ursolic Acid is found to have the following benefits:
- Collagen and elastin synthesis
- Repair photo-aged skin
- Product Highlights
The genus name Salvia, is derived from the Latin salvere, "to be saved", in reference to the healing properties of plant. Ursolic acid forms the oilresistant barrier on the skin. It inhibits the action of elastase in the skin, thereby preventing the enzyme from attacking structural proteins. Ursolic acid has been used to treat photo-aged skin because it helps prevent and improve the appearance of wrinkles and age spots by restoring the skin's collagen bundle structures and its elasticity.
Applications & Uses
- Markets
- Applications
- Baby Care Applications
- Bath & Shower Applications
- Hair Care Applications
- Oral Care Applications
- Other Beauty & Care Applications
- Skin Care Applications
- Treatment Product Applications
- Suggested Use Level
- 0.1 - 0.5 % w/w (Anti-aging)
- Applications
- Anti-inflammatory
- Anti-aging
- Collagen Build Up
- Formulation Guidelines
- Use stainless steel (SS316) vessels for production. Avoid contact with iron or copper
- Solubilize Sage Extract in one of the recommended solvents before adding it to emulsion below 40°C
- Nonionic and anionic emulsifiers are to be used
- Maintain the pH of the formulation slightly acidic, preferably between pH 5.0-6.0
- Sage Extract can be gelled using thickeners such as carbomer, acrylates copolymer and lecithin
- Opaque packaging is recommended for the finished product formulation
- Protect the finished product from exposure to direct heat and light
- Sage Extract is suitable for use in creams and translucent to opaque gels/ serums
- Sage Extract is not suitable for use in clear gels/serums/toners
- Use antioxidants and photostabilizers in the formulations
Properties
- Appearance
- Off white to creamish white powder
- Insoluble in
- Water
- Physical Properties
- Chemical Properties
- Typical Properties
- Other Properties
- Microbiological Values
- Solubility Data
Sage Extract Solubility Ratio Dimethylethanolamine 1:5 at 50°C Ethanol + DMEA (9:1) 1:10 at 50°C N-Methyl-2-Pyrrolidone 1:13 at 50°C
| Value | Units | Test Method / Conditions | |
| Ash Content | max. 5.0 | % w/w | USP <561> |
| Sieve Test (Passes Through #20 Mesh) | min. 100 | % w/w | USP <786> |
| Sieve Test (Passes Through #40 Mesh) | min. 90 | % w/w | USP <786> |
| Loose Bulk Density | 0.25 - 0.60 | g/ml | USP <616> |
| Sieve Test (Passes Through #80 Mesh) | min. 80 | % w/w | USP <786> |
| Loss on Drying (Dried at 105°C) | max. 5.0 | % w/w | USP <731> |
| Tapped Bulk Density | 0.40 - 0.80 | g/ml | USP <616> |
| Value | Units | Test Method / Conditions | |
| Oleanolic Acid Content (HPLC - on dry basis) | 15.0 - 25.0 | % w/w | SLL/STP-U-001 |
| Ursolic Acid Content (HPLC - on dry basis) | 60.0 - 75.0 | % w/w | SLL/STP-U-001 |
| Value | Units | Test Method / Conditions | |
| Alcohol Solubles (1% w/v solution in 95% v/v alcohol) | min. 50.0 | % w/w | SLL/STP-S-028 |
| Value | Units | Test Method / Conditions | |
| Arsenic Content | max. 1 | ppm (μg/g) | ICP-OES, SLL/STP-H-006 |
| Cadmium Content | max. 1 | ppm (μg/g) | ICP-OES, SLL/STP-H-006 |
| Lead Content | max. 3 | ppm (μg/g) | ICP-OES, SLL/STP-H-006 |
| Mercury Content | max. 0.1 | ppm (μg/g) | ICP-OES, SLL/STP-H-006 |
| Total Heavy Metals | max. 20 | ppm (μg/g) | USP <231> Method II |
| Value | Units | Test Method / Conditions | |
| Coliforms Count | max. 10 | cfu/g | BAM 2001, 8th Edition, Chapter 4 |
| Escherichia Coli | Negative | per 10g | USP <62> |
| Pseudomonas Aeruginosa | Negative | per 10g | USP <62> |
| Salmonella | Negative | per 10g | USP <62> |
| Staphylococcus Aureus | Negative | per 10g | USP <62> |
| Total Aerobic Microbial Count | max. 5000 | cfu/g | USP <61> |
| Total Yeasts and Molds Count | max. 100 | cfu/g | USP <61> |
Regulatory & Compliance
- Certifications & Compliance
- Chemical Inventories
Storage & Handling
- Shelf Life
- 5 Years
- Storage Condition
- Store at room temperature.