Sabinsa Cosmetics Sodium Ursolate

Identification & Functionality

Chemical Family: Organic Salts
INCI Name: Sodium Ursolate
Ingredient Origin: Natural Origin
Cosmetic Ingredients Functions: Conditioner
CAS No.: 220435-39-2
Technologies: Cosmetic Ingredients
Product Families: Cosmetic Ingredients — Functionals
Conditioners & Emollients
Product Details: Product code : 1938

Category : Intended for Cosmeceutical application

Botanical/Scientific name : Salvia officinalis

Plant part : Leaves

Preparation type : Extraction

Solvent used for extraction : Ethanol

Solvent used in manufacture : Acetone, Ethyl acetate

Final extract ratio : 70:1 to 75:1

Standardization : Sodium ursolate, sodium oleanolate

Excipient used : None

Features & Benefits

Benefit Claims: Anti-Irritant,
Antioxidant Properties
Labeling Claims: BSE-free,
GMO-free,
Natural,
Naturally Derived,
TSE-free
Benefits: Ursolic Acid is found to have the following benefits:

Collagen and elastin synthesis

Repair photo-aged skin
Product Highlights: The genus name Salvia, is derived from the Latin salvere, "to be saved", in reference to the healing properties of plant. Ursolic acid forms the oilresistant barrier on the skin. It inhibits the action of elastase in the skin, thereby preventing the enzyme from attacking structural proteins. Ursolic acid has been used to treat photo-aged skin because it helps prevent and improve the appearance of wrinkles and age spots by restoring the skin's collagen bundle structures and its elasticity.

Applications & Uses

Markets: Personal Care
Applications: Personal Care — Beauty & Care
Hair Care,
Skin Care
Application Format: Rinse Off
Hair Care Applications: Hair Conditioner
Suggested Use Level: 0.1 - 0.5 % w/w (Anti-aging)
Applications: Anti-inflammatory

Anti-aging

Collagen Build Up
Formulation Guidelines: Use stainless steel (SS316) vessels for production. Avoid contact with iron or copper

Solubilize Sage Extract in one of the recommended solvents before adding it to emulsion below 40°C

Nonionic and anionic emulsifiers are to be used

Maintain the pH of the formulation slightly acidic, preferably between pH 5.0-6.0

Sage Extract can be gelled using thickeners such as carbomer, acrylates copolymer and lecithin

Opaque packaging is recommended for the finished product formulation

Protect the finished product from exposure to direct heat and light

Sage Extract is suitable for use in creams and translucent to opaque gels/ serums

Sage Extract is not suitable for use in clear gels/serums/toners

Use antioxidants and photostabilizers in the formulations

Properties

Physical Form: Powder,
Solid
Appearance: White to off white powder
Chemical Properties
Physical Properties
Other Properties
Microbiological Values
Solubility Data: Sage Extract Solubility Ratio

Dimethylethanolamine 1:5 at 50°C

Ethanol + DMEA (9:1) 1:10 at 50°C

N-Methyl-2-Pyrrolidone 1:13 at 50°C

	Value	Units	Test Method / Conditions
Sodium Oleanolate Content (HPLC)	max. 30.0	% w/w	SLL/STP-S-032
Sodium Ursolate Content (HPLC - on dry basis)	70.0 - 100.0	% w/w	SLL/STP-S-032

	Value	Units	Test Method / Conditions
Loss on Drying (Dried at 105°C)	max. 3.0	% w/w	USP <731>
Moisture Content	max. 3.0	% w/w	USP <921>, KF Method

	Value	Units	Test Method / Conditions
Coliforms Count	max. 10	cfu/g	BAM 2001, 8th Edition, Chapter 4
Escherichia Coli	Negative	per 10g	USP <62>
Pseudomonas Aeruginosa	Negative	per 10g	USP <62>
Salmonella	Negative	per 10g	USP <62>
Staphylococcus Aureus	Negative	per 10g	USP <62>
Total Aerobic Microbial Count	max. 5000	cfu/g	USP <61>
Total Yeasts and Molds Count	max. 100	cfu/g	USP <61>

Regulatory & Compliance

Technical Details & Test Data

In Vitro Studies: Anti inflammatory Potential
In house studies reveal that it effectively helps in maintaining skin structural components such as elastin, collagen and hyaluronic acid.

The functional properties of these components are as follows:

Elastin : For skin elasticity

Collagen : For skin firmness and density

Hyaluronic acid : For skin strength that keep skin supple and toned

It helps in preventing and reversing skin aging by inhibiting hyaluronidase, collagenase and elastase enzymes.

The comparative anti-inflammatory potential of Sage Extract (Ursolic 90%) and Sodium
Ursolate has been shown.

Storage & Handling

Knowde Enhanced TDS