Knowde Enhanced TDS
Identification & Functionality
- Chemical Family
- Chemical Name
- Ingredient Origin
- Cosmetic Ingredients Functions
- CAS No.
- 8053-39-2
- EC No.
- 232-497-7
- Technologies
- Product Families
- Product Details
- Product code : 0851
- Category : Intended for Cosmeceutical application
- Botanical/Scientific name : Aesculus hippocastanum
- Plant part : Seeds
- Preparation type : Extraction
- Solvent used for extraction : Methanol
- Solvent used in manufacture : DM Water
- Final extract ratio : 33:1 to 35:1
- Standardization : Escin
- Excipient used : None
Features & Benefits
- Benefit Claims
- Product Highlights
Venocin is a natural extract from Horse Chestnut, a traditionally used botanical that supports healthy blood circulation. Laboratory and clinical studies have validated the anti-inflammatory role of Horse Chestnut extract. Escin, an active constituent of the extract inhibits enzymes such as hyaluronidase and collagenase, with potentially beneficial effects on the texture and appearance of the skin.
Applications & Uses
- Markets
- Applications
- Application Format
- Bath & Shower Applications
- Color Cosmetic Applications
- Hair Care Applications
- Skin Care Applications
- Treatment Product Applications
- Applications
- Supports blood circulation
- Wound healing support
- Anti-inflammatory
- Recommended Use Levels
- Recommended use levels in creams and lotions is 2 to 3%
- Tested formulations containing the ingredient showed no untoward effects on skin or eyes.
Properties
- Odor
- Characteristic odor
- Appearance
- Cream to pale brown powder
- Physical Properties
- Chemical Properties
- Typical Properties
- Other Properties
- Microbiological Values
Value | Units | Test Method / Conditions | |
Ash Content | max. 5.0 | % w/w | USP <561> |
Sieve Test (Passes Through #20 Mesh) | min. 95 | % w/w | USP <786> |
Loose Bulk Density | 0.15 - 0.50 | g/ml | USP <616> |
Sieve Test (Passes Through #40 Mesh) | min. 90 | % w/w | USP <786> |
Loss on Drying (Dried at 105°C) | max. 5.0 | % w/w | USP <731> |
Sieve Test (Passes Through #80 Mesh) | min. 75 | % w/w | USP <786> |
Tapped Bulk Density | 0.40 - 0.90 | g/ml | USP <616> |
Value | Units | Test Method / Conditions | |
Triterpene Glycosides as Escin (UV - on dry basis) | 90.0 - 110.0 | % w/w | USP |
Value | Units | Test Method / Conditions | |
Alcohol Solubles (1% w/v solution in 95% v/v alcohol) | min. 80.0 | % w/w | SLL/STP-S-028 |
Water Solubles (1% w/v solution in water) | min. 60.0 | % w/w | SLL/STP-S-028 |
Value | Units | Test Method / Conditions | |
Arsenic Content | max. 1 | ppm (μg/g) | USP <2232> |
Cadmium Content | max. 1 | ppm (μg/g) | USP <2232> |
Lead Content | max. 3 | ppm (μg/g) | USP <2232> |
Mercury Content | max. 0.1 | ppm (μg/g) | USP <2232> |
Value | Units | Test Method / Conditions | |
Coliforms Count | max. 10 | cfu/g | BAM 2001, 8th Edition, Chapter 4 |
Escherichia Coli | Negative | per 10g | USP <62> |
Pseudomonas Aeruginosa | Negative | per 10g | USP <62> |
Salmonella | Negative | per 10g | USP <62> |
Staphylococcus Aureus | Negative | per 10g | USP <62> |
Total Aerobic Microbial Count | max. 5000 | cfu/g | USP <61> |
Total Yeasts and Molds Count | max. 100 | cfu/g | USP <61> |
Regulatory & Compliance
- Certifications & Compliance
- Chemical Inventories
Technical Details & Test Data
- Efficacy Studies & Results
In published literature studies Horse Chestnut extract is reported to be beneficial to health in the following ways:
- Actives such as escin inhibit enzymes including collagenase, hyaluronidase, beta-glucuronidase, and elastase that catalyze the break down of the structural integrity of the veins and increase capillary permeability.
- Clinically proven to be beneficial to people suffering from varicose veins, spider veins, hemorrhoids and related circulatory problems or "chronic venous insufficiency" (CVI).
- In clinical studies, escin preparations have been successfully applied in the first stage of edema in cases of cellulitis of the thighs and breasts.
Packaging & Availability
- Regional Availability
Storage & Handling
- Shelf Life
- 5 Years
- Storage Condition
- Store at room temperature.