Knowde Enhanced TDS
Identification & Functionality
- Chemical Name
- Pharma & Nutraceuticals Functions
- CAS No.
- 9004-65-3
- EC No.
- 618-389-6
- Technologies
Features & Benefits
- Labeling Claims
Applications & Uses
- Markets
- Applications
- Manufacturing Technology
Properties
- Typical Properties
- Coating Properties
- Processing Parameters
- Particle Size Distribution
| Value | Units | Test Method / Conditions | |
| Bulk Density (Fluid Bed 1% Tylopur 606) | 0.41 | g/cm3 | — |
| Bulk Density (Fluid Bed 4% Tylopur 606) | 0.3 | g/cm3 | — |
| Heavy Metals | max. 20 | ppm | EP |
| Hydroxypropoxy Content | 7.0 - 12.0 | % | EP |
| Loss on Drying | max. 5.0 | % | — |
| Loss on Drying (Fluid Bed 1% Tylopur 606) | 0.5 | % | — |
| Loss on Drying (Fluid Bed 4% Tylopur 606) | 1.1 | % | — |
| Methoxy Content | 28.0 - 30.0 | % | — |
| pH | 5.0 - 8.0 | — | EP |
| Sulphated Ash /Residue On Ignition | max. 1.5 | % | EP |
| Visocity | 4.8 - 7.2 | mPas | — |
| Value | Units | Test Method / Conditions | |
| Inlet Air Flow (Coating Parameters) | Constant | m3/h | — |
| Inlet Air Flow (Coating Parameters) | 400.0 | m3/h | — |
| Inlet Air Temperature (Coating Parameters) | 80.0 | ⁰C | — |
| Nozzle Pressure Bar (Coating Parameters) | 0.65 | bar | — |
| Nozzle Pressure Bar (Coating Parameters) | 2.9 | bar | — |
| Pan Speed (Coating Parameters) | 22.0 | rpm | — |
| Pan Speed (Coating Parameters) | 11.0 | rpm | — |
| Spray Rate (Coating Parameters) | 4.3 - 6.1 | g/min | EP |
| Spray Rate (Coating Parameters) | 9 - 23 | g/min | EP |
| Tablet Bed Temperature during Coating | 38 - 40 | ⁰C | — |
| Tablet Bed Temperature during Coating | 35 - 40 | ⁰C | — |
| Tablet Bed Temperature during Coating | 40.0 | ⁰C | — |
| Value | Units | Test Method / Conditions | |
| Air Flow (Granulation Parameters for 4% Tylopur 606) | 40.0 | m3/h | — |
| Air Flow(Granulation Parameters for 1% Tylopur 606) | 40.0 | m3/h | — |
| Angle of Response (Fluid Bed 1% Tylopur 606) | 46.4 | ⁰ | — |
| Angle of Response (Fluid Bed 4% Tylopur 606) | 44.4 | ⁰ | — |
| Bowl (Granulation Parameters for 4% Tylopur 606) | 3.0 | L | — |
| Bowl (Granulation Parameters for1% Tylopur 606) | 3.0 | L | — |
| Disintegration Time | 728.0 | S | — |
| Dissolution(>80%) min | 10.0 | — | EP |
| Filter Cleaning / pause (Granulation Parameters for 1% Tylopur 606) | 5 / 0.5 | S | EP |
| Filter Cleaning / pause (Granulation Parameters for 4% Tylopur 606) | 5 / 0.5 | S | EP |
| Filter Pressure (Granulation Parameters for 1% Tylopur 606) | 1.5 - 2.0 | bar | EP |
| Filter Pressure (Granulation Parameters for 4% Tylopur 606) | 1.5 - 2.0 | bar | EP |
| Inlet Air Temperature (Granulation Parameters for 1% Tylopur 606) | 65.0 | ⁰C | — |
| Inlet Air Temperature (Granulation Parameters for 4% Tylopur 606) | 65.0 | ⁰C | — |
| Nozzle Position / Pressure (Granulation Parameters for 1% Tylopur 606) | 1.2mm / 1.5 bar | — | — |
| Nozzle Position / Pressure (Granulation Parameters for 1% Tylopur 606) | 1.2/ 1.5 | mm / bar | — |
| Nozzle Position / Pressure (Granulation Parameters for 4% Tylopur 606) | 1.2mm / 1.5 bar | — | — |
| Nozzle Position / Pressure (Granulation Parameters for 4% Tylopur 606) | 1.2/ 1.5 | mm / bar | — |
| Process time - Drying (Granulation Parameters for 1% Tylopur 606) | 8.0 | minutes | — |
| Process time - Drying (Granulation Parameters for 4% Tylopur 606) | 4.0 | minutes | — |
| Process time - Granulation (Granulation Parameters for 1% Tylopur 606) | 20.0 | minutes | — |
| Process time - Granulation (Granulation Parameters for 4% Tylopur 606) | 85.0 | minutes | — |
| Product Temperature - Drying (Granulation Parameters for 1% Tylopur 606) | 31.0 | ⁰C | — |
| Product Temperature - Drying (Granulation Parameters for 4% Tylopur 606) | 29.0 | ⁰C | — |
| Product Temperature - Granulation (Granulation Parameters for 1% Tylopur 606) | 25.5 | ⁰C | EP |
| Product Temperature - Granulation (Granulation Parameters for 4% Tylopur 606) | 28.3 | ⁰C | EP |
| Product Temperature - warm up (Granulation Parameters for 1% Tylopur 606) | 31.0 | ⁰C | EP |
| Product Temperature - warm up (Granulation Parameters for 4% Tylopur 606) | 31.0 | ⁰C | — |
| Spraying Speed (Granulation Parameters for 1% Tylopur 606) | 5.4 - 11 | g/min | — |
| Spraying Speed (Granulation Parameters for 4% Tylopur 606) | upto 12 | g/min | — |
| Value | Units | Test Method / Conditions | |
| Particle Size (x50) (Fluid Bed 1% Tylopur 606) | 104.0 | µm | — |
| Particle Size (x50) (Fluid Bed 4% Tylopur 606) | 188.0 | µm | — |
Regulatory & Compliance
- Certifications & Compliance
- Chemical Inventories
- Grade
Packaging & Availability