SEPPIC INC
SEPPIC INC Heterosides
Heterosides is a highly purified water-soluble extract of Centella asiatica for skin barrier function improvement. This product provides stratum corneum formation enhancement, tight junctions reinforcement, differentiation normalization and activation of the deeper layers of the epidermis. Its anti-wrinkle effect has been recently demonstrated on the crow’s feet. Significant TEWL reduction on volunteers with a dry skin has been also observed. This is a titrated blend of the glycosylated triterpens Asiaticoside and Madecassoside. This is an active ingredient for use in intense skin care applications for dry and dehydrated skin, as well as mature skin. It comes as a crystalline powder.
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Features And Benefits
Ingredient Claims
Preservative-free
QD Additive
End Use Claims
Skin barrier
Wrinkle reduction
Wrinkle prevention
Regional Availability
North America
Europe
Asia Pacific
Regulatory Status
China Compliant
Product Characteristics
Origin
Plant Origin
Physical Form
Powder
Physical And Chemical Properties
Active content
≥ 70%
Formulation Conditions
Use Level
0.2-0.5%
Soluble in
Water
Technical product information
Product Benefits
- TEWL reduction: -8% vs Placebo (D28)
- Smoothing effect:-36% vs Placebo(D28)
- Anti-wrinkle effect: -19% vs Placebo(D56)
Mode of Action
- Reinforce the "mortar" (Ceramides-2: +44%)
- Strenghten the "brick" envelop (Involucrin, Loricrin, Filaggrin)
- Boost cell cohesion (tight junctions)
- Moisturize (AQP3: +29%) & soothe (PGE-2, IL-8, IL-1α)
- It prevents dehydration by reactivating all the natural mechanisms that restructure and pamper the skin barrier
- It erases fine lines and wrinkles by enhancing water retention and dermis scaffold

SEPPIC INC Heterosides
30, 2 Bridges Road, Suite 210
Fairfield, NJ 07004, United States