Knowde Enhanced TDS
Identification & Functionality
- Chemical Name
- Pharma & Nutraceuticals Functions
- CAS No.
- 9003-39-8
- Molecular formula
- (C6H9NO)n
- EC No.
- 618-363-4
- Technologies
- Product Families
- Chemical Structure
Features & Benefits
- Features
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Solubility
The polyvinylpyrrolidone molecule contains both hydrophilic and lipophilic groups, and is soluble in water and a variety of organic Solvent. Easier to dissolve in organic solvents with strong polarity, and more difficult to dissolve in weak or non-polar organic solvents.
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Molecular Weight
The molecular weight of polymer PVP is generally indicated by weight average molecular weight or number average molecular weight.The average molecular weight MW, which is the weight of the molecule measured by the light scattering method.
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Hygroscopicity
Polyvinylpyrrolidone has strong water absorption and moisture retention, and polyvinylpyrrolidone of different molecular weights
(K25, K30, K90) basically have little difference in hygroscopicity, which is very important in many applications.
The water absorption rate of PVP in the air increases with the increase of relative humidity.-
Complexation
PVP can be combined with a variety of substances, especially those containing hydroxyl, carboxyl, amino and other active chlorine-containing compounds or Simple substance form complexes, for example, it can form with many mycins, viruses, medicines and toxic chemicals
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The complex is less toxic and irritating.
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PVP and elemental iodine form PVP-I through complexation, which is an efficient and spectral disinfectant.
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Complexing with insoluble active ingredients to form water-soluble complexes, making absorption easier, medical technology used as a co-solvent, slow-release agent, etc.
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It has strong complexing power with a few substances (such as polyphenols). In neutral and acidic substances, the form precipitation, this feature can remove polyphenols and anthocyanins from solutions and beverages, but the use of insoluble Sexual PVP works better.
Note: Strong alkaline substances (such as potassium carbonate or sodium hydroxide) can crosslink PVP, especially at high temperatures, which are more likely to occur.
Under extreme conditions, it can thicken medicinal liquid preparations and hinder the release of active ingredients.Quality, colloidal protection, film-forming, cohesiveness, hygroscopicity, solubilization or cohesion, but the most of it is unique, so people pay attention to its excellent solubility and physiological compatibility. In synthesis in polymers, like PVP, it is soluble in water and most organic solvents, with low toxicity and physiological characteristics.
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Applications & Uses
- Markets
- Applications
- Uses
PVP is widely used as an excipient for pharmaceutical preparations, and its specific applications are as follows
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Used as a binder for preparations
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Co-precipitating agent
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As a co-solvent or crystal formation inhibitor in injections
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Coating or film-forming agent
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Delay agent , Controllable release of sustained-release drugs can prolong the action time of drugs
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Artificial vitreous and cornea
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Surgical bandage
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PVP iodine disinfectant.
In addition, PVP can also be used as a colorant and X-ray contrast agent; it can be used in various dosage forms such as tablets, granules, liquids, etc.,
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- Applications
Good compatibility is rare, especially in medicine, food, cosmetics, which are closely related to people's health In related fields.
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Medicine & Health
PVP has excellent physiological inertia, does not participate in human metabolism, and has excellent biocompatibility. Does not cause any irritation to skin, mucous membranes, eyes, etc. Pharmaceutical-grade PVP is the three major medicinal uses advocated internationally one of the new excipients, it can be used as a binder for tablets and granules, a co-solvent for injections, and an aid for capsules. Flow agent; detoxifier for eye drops, delay agent, lubricant and coating film-forming agent, dispersant for liquid preparations It can also be used as a stabilizer for enzymes and heat-sensitive drugs, and can also be used as a cryopreservative. Used for contact lenses, can increase Its hydrophilicity and lubricity.
- Water treatment membrane
Polyvinylpyrrolidone is not only an excellent material for modified membrane materials in the water treatment industry, but also excellent Pore-forming agent, therefore, has been widely used in the water treatment industry. With the progress and development of society,Due to its excellent effluent quality and wide applicability, membrane separation technology has become the best in wastewater recycling plants. One of the most concerned water treatment technologies today. As a porogen, PVP has many excellent properties. It is chemically stable and can have Effectively control the size of the membrane pore size and the distribution of pores, increase the density of the membrane pores, and improve the permeability of the membrane Improve the hydrophilicity of the membrane surface and good biocompatibility. PVP can be used in the manufacture of various functional membrane materials to improve membrane selectivity. In various ways in the process of preparing ultrafiltration and nanofiltration membranes from polymer materials, PVP of various molecular weights is widely used as Pore-forming agent, so as to obtain membrane separation materials with various separation accuracy and different adaptability, It is widely used in seawater desalination, water treatment, product concentration and purification. The development of environmental water treatment business has a greater demand for support for PVP products. RO membrane separation method sewage treatment and purification treatment process has become the mainstream process in this industry today. Among them, the PVD membrane for nanofiltration or ultrafiltration is an important part of the membrane industry, and its film-forming porogen K30. At present, there is already a consumption of 3000MT/a. With the increasing scarcity of water resources in the world Increase, the economic value of water recycling has become increasingly prominent, and major countries’ environmental governance Strengthen, in the next 3-5 years.Form complexes, mainly used as food clarifiers such as beer, fruit juice, wine, etc.
- Food processing and stabilizers
PVP can form complexes with specific polyphenol compounds (such as tannins) Play a clarification and anti-coagulation effect in the material. Add 0.01%-0.02% soluble PVP in the fermenter, can effectively reduce its freezing point. PVP can also be used in the production process of wine and vinegar play the same role use. Cross-linked PVP is particularly widely used in beer and tea beverages. Polyphenols in beer can Combines with the protein in beer to generate tannin macromolecular complexes, which will seriously affect the flavor of beer. And shorten its warranty period, and cross-linked polyvinylpyrrolidone (PVPP) can interact with the tannic acid in beer. it complexes with anthocyanins to clarify the beer, improve the storage stability of the beer, and extend the shelf life. In tea beverages, the use of PVPP can appropriately reduce the content of tea polyphenols, and PVPP does not remain in tea beverages. The material can be reused, which greatly reduces the cost.
- Daily cosmetics
In the consumption structure of PVP, the cosmetics industry in developed countries accounts for 30%-50%, and my country accounts for 70%-80%. Because PVP has extremely low toxicity and physiological inertia, it has no irritation to the skin and eyes.There are long-term use records in the domain, so it is safe to use in cosmetics. In daily cosmetics, PVP and copolymers have good dispersibility and film-forming properties. PVP has the function of protecting colloid in the emulsion and can be used in fatty and non-fatty pastes, it is used as styling liquid, hair spray and mousse styling machine, hair care, Sunscreen agent, foam stabilizer in shampoo, wave setting agent and dispersant and affinity in hair dye agent. Adding PVP to creams, sunscreens, and depilatory agents can enhance the moisturizing and lubricating effects.
- Detergent
PVP has anti-dirt re-precipitation performance and can be used to configure transparent liquid or heavy-dirt detergents. Adding PVP to the agent has a good anti-turning effect, and can enhance the washing ability, when washing the fabric it can prevent synthetic detergents from irritating the skin, especially for synthetic fibers. This performance is better than that of carboxymethyl fibers. CMC detergents are more prominent. PVP can be compounded with borax as a phenolic disinfectant cleaner the active ingredients in the formula. In the detergent compounded with PVP and hydrogen peroxide solid, it has the advantages of drifting and killing diseases.
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Textile
PVP has a good affinity with many organic dyes. It can interact with polyacrylonitrile, ester, nylon and fiber. The combination of hydrophobic synthetic fibers such as materials to improve dyeing power and hydrophilicity, after graft copolymerization of PVP and nylon, the fabric produced has improved wet wrinkle resistance and moisture resistance.
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Coatings and pigments
Coating paints and coatings with PVP to form a transparent film without affecting the natural color, improving the gloss and gloss of the coatings and pigments.Dispersibility, improve thermal stability and improve the dispersibility of inks and inks, etc.
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Polymer surfactants
As a polymer surfactant, polyvinylpyrrolidone can be used as a component in different dispersion systems. Powders, emulsifiers, thickeners, leveling agents, particle size regulators, anti-reprecipitation agents, coagulants, aids Solvents and detergents.
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Properties
- Soluble in
- Chloroform, Isopropanol, Glycerin, Propylene Glycol, Methanol, Dichloromethane, Cyclohexanol, N-Propanol, Polyethylene Glycol 400, Waterfree Alcohol, N-Butanol, Triethanolamine
- Insoluble in
- Acetone, Xylene, Toluene, Diethyl Ether, Cyclohexane, Liquid Paraffin, Pentane, Carbon Tetrachloride
- Typical Properties
| Value | Units | Test Method / Conditions | |
| Water soluble (20°C) | min. 10 | g/100 mL | — |
Regulatory & Compliance
- Certifications & Compliance
Packaging & Availability
- Packaging Type