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Sidley Chemical COA-LH 22

Sidley Chemical COA-LH 22 is a normal disinterating property, used while no need of strong cohesive force.

Chemical Name: Low-Substituted Hydroxypropyl Cellulose

CAS Number: 9004-64-2

Functions: Disintegrant

Synonyms: 2-Hydroxypropyl cellulose, Cellulose hydroxypropyl ether, Hydroxypropyl cellulose, Hydroxypropyl cellulose ether, Hydroxypropyl ether of cellulose, O-(2-Hydroxypropyl)cellulose, O-(Hydroxypropyl)cellulose, Oxypropylated cellulose

Technical Data Sheet
  • TypeDocument Name
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Knowde Enhanced TDS

Identification & Functionality

Pharma & Nutraceuticals Functions
CAS No.
9004-64-2
EC No.
618-388-0

Features & Benefits

character
  • White or off-white powder,no smell,tasteless;insoluble in ethanol, acetone and ether.
Execution Standard
  • Execution standard:CP2015,USP

Applications & Uses

Application
  • Mainly used as disintegrant and adhesive of solid dosage. Its powder has a large surface area and porosity so that accelerates the absorption temperature,increasing the swelling property which makes tablet easy to collapse. In the meanwhile, a larger mosaic effect among its rough structure,drugs and particles improvs the hardness and gloss of the tablet. To the drug that cannot easily be shaped, it will promote it molding, improve its hardness. To the drug with poor disintegrating property, it will accelerate the collapse so that improve the dissolution to enhanced bioavailability.

Properties

Appearance
Conforms
Typical Properties
ValueUnitsTest Method / Conditions
CategoryPharmaceutic adjuvant--
Arsenic Contentmax. 0.0002--
Heavy Metalsmax. 20--
Assay7.0-9.9%-
Assay8.2%-
Iron Contentmax. 0.010--
Particle45μm-
IdentificationConforms--
PHPH 5.6--
Chlorides0.06%-
Loss on Drying5.5%-
Residue on Ignition0.3%-
Particle SizeConforms--

Packaging & Availability

Packaging Type
Packaging
  • Package - 25kg/barrel;25kg/bag