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HYDRO-B18

Socri - Greengredients HYDRO-B18 is a cutting-edge water-soluble form of natural 18-ß-glycyrrhetinic acid which - in its original form - has poor bioavailability and very low water solubility.

INCI Name: Glycyrrhetinic Acid, Polyglyceryl-6 Caprylate, Proline

Functions: Anti-Inflammatory, Soothing Agent

Ingredient Origin: Natural Origin, Non-Animal Origin, Plant Origin

Labeling Claims: Biodegradable, Clean at Sephora, Halal, Natural, Naturally Derived, Palm Oil-free, Palm free, Plant-Based, Ulta Beauty's Conscious Beauty, Vegan

Certifications & Compliance: COSMOS, Halal, NaTrue

Benefit Claims: Age & Dark Spot Reduction, Anti-Inflammatory, Anti-Itching, Broad pH Stability, Irritation Reduction, Oxidation Protection, Soothing, Suitable for Sensitive Skin

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Knowde Enhanced TDS

Identification & Functionality

Carrier
Cosmetic Ingredients Functions

Features & Benefits

Benefits
  • 18-ß-glycyrrhetinic acid is regarded as one of the most effective functional ingredients in nature with marked anti-inflammatory and soothing activity.
  • It finds extensive use in the pharmaceutical sector and is often used in its derived salified version.
  • HYDRO-B18® contains 10% of free and intact 18-ß-glycyrrhetinic acid delivered in a 100% plant-derived medium.

Applications & Uses

Application Format
Skin Care Applications
Sun Care Applications
Treatment Product Applications
Use Level
1%
Application
  • Skincare : transparent gels and emulsions for sensitive and irritated skins.
  • Suncare : after sun transparent gels and emulsions.

Properties

Physical Form
Appearance
Clear liquid
Odor
Characteristic
Microbiological Values
ValueUnitsTest Method / Conditions
Total Bacteriamax. 100CFU/g-
Total Moldsmax. 100CFU/g-
Characteristics
ValueUnitsTest Method / Conditions
Dry Residue55 - 57%-
Specific Gravity (at 25°C)1.13 - 1.15g/ml-
Heavy Metalsmax. 10ppm-
pH (5% water solution, at 25°C)7.5 - 9.5--
SolventWater--
Solubility

Transparent soluble in demineralized water at pH 7-9. The presence of surfactants allows to widen its transparent solubility in a wider pH range.

Properties
  • Transparent soluble in demineralized water at pH 7 - 9. The presence of surfactant allows widening its transparent solubility in a wider pH range.
  • 100% plant-derived and palm-free.
  • Cortisone - like ingredient : cortisone-like ingredients such as glycyrrhetinic acid, relieves skin irritations without the typical side effects of corticosteroids. It can be applied daily as part of a preventive skincare regime for sensitive skin and especially in skincare products for infants who have not yet developed a protective hydro-lipid film or acid mantle.
  • Anti itching action : Glycyrrhetinic acid reduces the rise of the itching. In particular, it has been shown the role of glycyrrhetinic acid in reducing chronic pruritus by reducing the level of leukotrienes produced.
  • Anti melanogenic action : In vitro studies on cell lines have shown that treatment with glycyrrhizin and its aglycone, glycyrrhetinic acid both before and during sun exposure - prevents oxidative damage.

Regulatory & Compliance

Certifications & Compliance

Technical Details & Test Data

Composition
INCI Name Contents (%)
Aqua 45 - 50
Polyglyceryl-6 Caprylate 30 - 35
Glycyrrhetiinic Acid 10
Proline 10

 

Test

In-vivo tests demonstrate soothing activity:

  • 16% TEWL - after 2 applications of a cream containing 1% HYDRO-B18® on SDS-induced erythema
  • 21% erythema index after 3 applications of a cream containing 1% HYDRO-B18® on SDS-induced erythema
  • In-vivo comparative tests show that HYDRO-B18® is more effective in treating erythema than standard Bisabolol and Ammonium Glycyrrhizate.

Storage & Handling

Shelf Life
36 Months