Knowde Enhanced TDS
Identification & Functionality
- Ingredient Name
- Mineral Type
- Food Ingredients Functions
- Pharma & Nutraceuticals Functions
- Ingredients
- Calcium
Features & Benefits
- Benefit Claims (Health)
- Labeling Claims
- Food Ingredients Features
- Calbon N prevents the loss of Bone Mineral Density (BMD)
fects of treatment on BMD In a 6-month study Calbon N increased Spine Bone mineral density.
Effects on bone markers Positive effects on bone markers are statistically significant within 6 months after starting the trial.
Adverse effects Calbon N is well tolerated and does not cause any gastrointestinal symptoms.
Study protocol The equivalent of 500 mg of calcium was given on a daily bases. Calbon N was given in a hard gelatine capsule, each capsule containing the equivalent of 125 mg calcium and 56 mg phosphorus.
Bone Mineral Density Dual energy X-ray absorptiometry (DEXA) was used to assess bone density. This technique is widely used because of its ability to assess bone mass at both axial and appendicular sites, its high reproducibility and the low doses of radiation associated with the measurement. Therefore, it represents one of the most reliable techniques to assess BMD at the spine nowadays
Applications & Uses
- Markets
- Food & Nutrition Applications
- How to use CalbonN
Calbon N can be used as an ingredient for various food applications without disadvantageous effects on taste or structure. It is advised to add the Calbon N mesh 200 to the basic food products. Calbon N can be added to cereal products, like flour prepared mixes, baked goods, breakfast cereals and pasta’s, and dairy products as for example yogurt or ice cream. Furthermore, Calbon N can be taken at meals as a calcium additive in various taylormade shapes, such as tablets, hard gelatine capsules, chewable tablets or oral liquid (high suspension powder). Calbon N mesh 50 for example is extremely suitable for producing tablets because of its direct compressibility. As an oral liquid it is accessible for people having difficulties swallowing tablets, often elderly people
Properties
- Typical Properties
| Value | Units | Test Method / Conditions | |
| Calcium | 32 | % | |
| Protein | 10 | % | |
| Moisture | 1.5 | % | |
| Phosphorus | 14 | % |
Regulatory & Compliance
Technical Details & Test Data
- Why calcium and phosphorus
Calcium and phosphorus are essential to all life, animal and vegetable, single-celled and multi-celled organisms. Although the inorganic salts, commonly called minerals, comprise a small percentage of total body weight they are as important to the wellbeing as the proteins, carbohydrates and fats that provide energy. Children require calcium and phosphorus in their diet for normal growth, adults require it for maintenance and replacement. Pregnant and lactating women require larger quantities of calcium and phosphorus than other adults because a portion of their intake is utilized by the growing fetus or child
Calcium also plays an important role in the prevention of osteoporosis, in the coagulation of blood, and for the proper functioning of the nervous system. Osteoporosis is a bone disease that has been identified as a major health problem throughout the world.
- Why does CalbonN score so well
Calbon N is produced by a manufacturing process designed to ensure that the components retain their natural form and physiological properties. The active constituent is not a single chemical entity. It is a mixture of which the main component is a calcium hydroxy-apatite concentrate. This salt is present in microcrystalline form in combination with proteins. A positive fact of bone derived calcium supplements is that they contain phosphorus. Next to calcium, phosphorus is important for healthy bones. Studies indicate that ingestion of a combination of calcium and phosphorus results in better bone building than ingestion of calcium alone. Calcium on its own will bind phosphorus (from food) in the gut, and prevent that the phosphorus will be absorbed in the circulation where it comes available for bone building1 . (1 Robbert P. Heaney, MD, FACN. Journal of the American College of Nutrition, vol. 21, no. 3, 239-244 (2002))
Figure 1 Effect of calcium intake on available phosphorus for calcium from calcium citrate or calcium carbonate
Source: Robbert P. Heaney, MD, FACN. Journal of the American College of Nutrition, vol. 21, no. 3, 239-244 (2002)Figure 2 Effect of calcium intake on available phosphorus for calcium from calcium phosphorus
Source: Robbert P. Heaney, MD, FACN. Journal of the American College of Nutrition, vol. 21, no. 3, 239-244 (2002)