Knowde Enhanced TDS
Identification & Functionality
- Chemical Name
- Pharma & Nutraceuticals Functions
- CAS No.
- 9067-32-7
- EC No.
- 618-620-0
- Technologies
Features & Benefits
- Medical Grade Hyaluronic Acid Functions
- Viscoelasticity, protecting corneal endothelium
- Lubricating, viscoelasticity, repairing damage cartilage, inhibition of inflammation, pain relief, etc.
- Properties of good biocompatibility and degradability of HA and its derivatives
Applications & Uses
- Markets
- Dosage Form
- Applications
Medical Devices:
- Ophthalmic surgery (viscosupplementation)
- Eye drops for dry eye (eg. artificial tears)
- Intra-articular injections
- Topical preparations for wound and burns healing
- Intradermal injections for esthetic correction
- Anti-adhesive and shape keeping products for thoracic and abdominal surgery
- Anti-adhesive wound healing products
- Bandages with exudates absorbing capacity
Remedies /Drugs:
- Sodium hyaluronate on its own as active substance
- Cartilage (joint) and tendon disorders
- Wound and burns healing preparations
- Sodium hyaluronate in combination with other active substances
- Anti-cancer preparations
- Wound and burns healing preparations
- Preparations for reduction of scar formation
- Eye drops
- Topical anti-inflammatory and analgesics preparations
- Cartilage (joint) and tendon disorders
- Nutraceuticals supporting the treatment of skeleton or prevention of skeleton disorders
- Preparations for liver regeneration
Issue Engineering:
- Artificial skin grafts for plastic and reconstruction surgery
- Replacement of injured cartilage, artificial cartilage grafts
- Adipose tissue replacement
- Aorta and large venous grafts industry
- Artificial skin for the test of cosmetic raw material
- Artificial bone grafts
- Support for the growth of soft tissue grafts
Application in Biotechnology and Molecular Biology
- Component of special cell culture medium
- Biotinylated for detection of hyaluronan binding proteins
- Supporting material for gene transfer
Other Biological Applications
- Sperm separation according to their mobility
- Medium for in vitro ovum fertilization. For parenteral preparations or oral preparations not including intra-articular and intra-ocular preparations. It can be used in eye drops, contact lens solutions, topical preparations for the wound or burn healing, medical lubricants, etc.
Properties
- Physical Form
- Appearance
- White Powder
- Typical Properties
| Value | Units | Test Method / Conditions | |
| Appearance of Solution (A600nm) | max. 0.01 | — | — |
| Ph (5mg/ml Solution) | 5 - 8 | — | — |
| Molecular Weight | 10 - 3000 | K Da | — |
| Sulfated Glycosaminoglycans | max. 1 | % | — |
| Nucleic Acid (A260nm) | max. 0.5 | — | — |
| Protein | max. 0.1 | % | — |
| Chlorides | max. 0.5 | % | — |
| Iron | max. 80 | ppm | — |
| Heavy Metals | max. 20 | ppm | — |
| Loss On Drying | max. 20 | % | — |
| Bacterial Counts | max. 100 | cfu/g | — |
| Mold And Yeast | max. 100 | cfu/g | — |
| Sodium Hyaluronate | 95 - 105 | % | — |
| Glucuronic Acid | min. 42 | % | — |
Regulatory & Compliance