Knowde Enhanced TDS
Identification & Functionality
- Ingredient Origin
- Animal Feed & Nutrition Functions
- Food Ingredients Functions
- Ingredients
- Lactose, Calcium Carbonate
Features & Benefits
- Food Ingredients Features
- Key Features
The Pioneer in Postbiotics
The gut feeling you can trust.
LBiome™ is a human strain-derived, heat-treated postbiotic (Lactobacillus LB) that has been used as a digestive aid for over a century. Researched in postbiotic form for over 100 years, LBiome is the “Pioneer in Postbiotics,” with 12 published clinical studies showing digestive health support for both adult and pediatric populations. LBiome provides the digestive benefi ts of a probiotic and the formulation fl exibility of a spore, with none of the stability or manufacturing concerns.
How does LBiome work?
LBiome is a postbiotic, so there are no live organisms present. However, LBiome heat stabilized cells and metabolites continue to provide quick and effi cacious digestive health benefi ts. LBiome cells adhere to the gut lining, supporting a healthy bacterial balance in the digestive system, all while simultaneously strengthening the gut lining by supporting a healthy brush border and tight junctions. These mechanisms of action produce fast results for calming lower GI upset, as seen in the many published LBiome clinical studies.*
- Postbiotics
- Pediatric Digestive Health
- Digestive Health
- Gut Immunity
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Applications & Uses
- Markets
- Applications
- Food & Nutrition Applications
- Suggested use
Take 170 mg (10 billion cells) twice daily
Properties
- Solubility
- Appearance
- Free flowing powder
- Odor
- Characteristic slight bouillon odor, Slight bouillon odor
- Microbiological Values
- Specifications
- Note
Antibacterial activity against Salmonella - Viability decreased = 4 log
Inhibition of internalization of Salmonella enterica serovar Typhimurium into Caco-2 - Score = 90%
| Value | Units | Test Method / Conditions | |
| Cell count | min. 60 billion cells per gram | — | — |
| Detection of coagulase-positive staphylococci | Absent in 10g | — | — |
| Detection of Enterobacter | Absent in 1g | — | — |
| Detection of Escherichia coli | Absent in 10g | — | — |
| Detection of Listeria monocytogenes | Absent in 25g | — | — |
| Detection of Salmonella | Absent in 25g | — | — |
| Total Aerobic Count | max. 5 x 10² | cfu/g | — |
| Yeast and Mold Count | max. 5 x 10² | cfu/g | — |
| Value | Units | Test Method / Conditions | |
| Loss on Drying | max. 6.5 | % | — |
| Particle Size (min. 80% of particles) | 125 - 500 | um | — |
| pH Value | 4.5 - 5.5 | — | — |
| Water Activity | 0.87 | — | — |
Regulatory & Compliance
- Certifications & Compliance
Technical Details & Test Data
- US Claims
• Digestive health for the whole family: Researched for safety and efficacy in children (1 month+)
• Helps calm digestive upset*
• Starts working the first day you take it*
• Helps support bowel regularity*
• Helps support abdominal comfort and reduce occasional bloating*
• Promotes a healthy bacterial balance in the digestive system*
• Helps support a healthy gut barrier and gut immunity*
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. - LBiome™ helps improve digestive outcomes quickly from multiple causes
Subjects with Digestive
ComplaintTreatments Average Daily Dose Statistically Significant
Digestive BenefitsReferences 71 children
(1 to 48 mo)3 sachets (10 B cells each)
during first 24 hrs followed
by 2 sachets daily with ORS
vs. placebo30 B cells/day
10 B cells/dayYes Boulloche et al. 1994 73 children
(3 to 24 mo)5 sachets (10 B cells each)
over 48 hrs with ORS vs.
placebo25 B cells/day Yes Simakachorn et al. 2000 80 children
(3 to 48 mo)6 sachets (20 B cells each)
over 35 hours with ORS vs.
placebo82 B cells/day Yes Salazar-Lindo et al. 2007 80 children
(1 to 12 mo)8 sachets (10 B cells each)
over 96 hours with ORS20 B cells/day Yes Lievin-Le Moal et al. 2011 184 adults 2 capsules (5 B cells each)
daily during one week of
antibiotic treatment10 B cells/day Yes Jason et al. 2010 137 adults 4 week course of 2 capsules
(5 B cells each) twice a day20 B cells/day Consistency, abdominal
comfort and bloatingXiao et al. 2003 297 adults 4 week course of 2 capsules
(5 B cells each) twice a day20 B cells/day Frequency and abdominal
comfortTarrerias et al. 2011
Storage & Handling
- Shelf Life
Shelf Life is not less than 24 months at time of manufacture. Product must have 75% or more of shelf life remaining at time of delivery to Stratum.