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BIOLIN/P

BIOLIN/P is a natural prebiotic that has been proven to help rebalance the skin’s microbiota. The prebiotics are based on inulin extracted from chicory root and they work by selectively supporting protective organisms to help restore the microbiota layer and prevent certain skin conditions. BIOLIN/P offers the benefit of barrier protection to both skin and scalp. It is a well-suited addition to a microbiome-based product. BIOLIN/P is a product from Gobiotics.

INCI Name: Alpha-Glucan Oligosaccharide, Inulin

Functions: Prebiotic, Protective Agent, Skin Barrier Protectant

Ingredient Origin: Natural Origin

Labeling Claims: Clean at Sephora, Credo Clean Standard, Natural, Naturally Derived, Ulta Beauty's Conscious Beauty

Benefit Claims: Barrier Function Improvement, Skin Barrier, Skin Microbiome, Skin Protection

    Knowde Enhanced TDS

    Identification & Functionality

    Ingredient Origin

    Features & Benefits

    Key Benefits
    • Clinically proven to prevent reoccurrence of severe skin conditions
    • Reinforces the protective skin microbiota
    • Natural inulin and a-glucan-based prebiotic
    • Derived from chicory root, sugar beets and wheat
    • Selectively supporting beneficial organisms
    • Globally compliant (including China)

    Applications & Uses

    Use Level
    0.5 – 3%
    Formulation Guidelines
    • Recommended dosage: 0.5 – 3%
    • pH range: 4.3 – 10.0
    • Temperature: <60°C for durations up to 8 hours
    • Add to and dissolve in water phase
    • Can be dispersed in oil and esters
    • Prolonged and high temperature exposure can lead to slight yellowing
    • Avoid strong oxidizing agents (e.g. peroxides)
    • Avoid reducing agents

    Properties

    Physical Form
    Odor
    Odorless
    pH
    4.3 – 10.0

    Technical Details & Test Data

    Combatting Recurrence of Severe Skin Conditions

    Skin conditions are generally caused or sustained by microbiota imbalances characterized by dominance or infections by certain organisms, such as C. albicans, S. aureus, etc. The treatments for these conditions can be disruptive, leaving skin vulnerable for new infections due to the absence of a strong protective microbiota. BIOLIN/P can help restore the microbiota quickly and protect against new or reoccurring infections.

    BIOLIN/P - Combatting Recurrence of Severe Skin Conditions

    Clinical trial involving 15 atopic babies suffering from severe diaper rash caused by C. Albicans infection. Babies returned to hospital regularly for cortisone treatments. When using standard diaper rash creams afterwards the condition returned (left), whereas with application of same cream with 1.5% BIOLIN/P the condition did not reoccur (right). No conclusion is for a baby not brought back for evaluation.

     

    Before Trial

    BIOLIN/P - Combatting Recurrence of Severe Skin Conditions - 1

     

    Evaluation after 1st and 2nd use peroid

    BIOLIN/P - Combatting Recurrence of Severe Skin Conditions - 2

    BIOLIN/P - Combatting Recurrence of Severe Skin Conditions - 3

    Clinical trial involving 50 patients suffering from discomfort due C. Albicans infection. Use of 1.5% BIOLIN/P containing hygiene wash, 2 times 2-4 weeks use with 4-6 weeks rest period in-between. Dermatological and self-assessment shows no discomfort when using BIOLIN/P containing wash (right) compared to initial situation (left).

     

    Increase in Hydration

    BIOLIN/P - Combatting Recurrence of Severe Skin Conditions - 4

     

    Decrease in TEWL

    BIOLIN/P - Combatting Recurrence of Severe Skin Conditions - 5

    Clinical trial involving 50 patients suffering from dry and irritated skin due to diabetic conditions, often characterized by C. Albicans and S. Aureus infections. 4 week application of cream combining benfothiamine and BIOLIN/P, showing overall improvement of skin health, including increased skin hydration, decreased TEWL and increased sebum content.