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Gynostemma (Jiaogulan, Gynostemma pentaphyllum, GpM) is a Chinese medicinal herb. It is also called “Amachazuru” in Japanese and “Panjakun” in Thai. Gynostemma pentaphyllum is in the family Cucurbitaceae. It is a kind of Perennial lianas with vine-like stems and has oval leaves with serrated, white hairs and five-leaf clusters. Gynostemma grows abundantly in south-central China. The leaf is always used to make medicine. Jiaogulan is sometimes known as “Southern Ginseng” because it grows in Southern China and has a similar effect as ginseng. Gynostemma is a kind of herbal tea which is currently being promoted and sold. It is good for health and beauty. Gynostemma is always used for high blood pressure, high cholesterol, and improving heart health. It is also beneficial to prime the immune system, improves memory, and anti-hair loss. Some people use gynostemma pentaphyllum as an antioxidant, anti-aging agent, and detoxifying agent.