Products in Pharmaceutical Manufacturing: Capsules

KLEPTOSE® LINECAPS Pea Maltodextrin Cyclodextrin can be used as a solubilizer, stabilizer and taste-making agent in pharma oral dosage applications. Applications Swallowable, chewable and effervescent tablets Lozenges Hard and soft capsules Orally dissolving films Blends Granules Pellets premix Medicated confectionery Syrups Suspensions Liquids Cream Paste Semi-solids

NUTRIOSE® FM06 Dextrin can be used to add dietary fiber to capsules, films, granules, lozenges and other pharmaceutical applications. Benefits BSE-free Gluten-free Halal and Kosher certified Melamine-free Non-GMO Non-Hazardous TSE-free Vegan Features Chemical stability Easy dispersability

Kollisolv® PEG 300, a polyethylene glycol, serves as a versatile solvent, solubilizer, carrier, and suppository base in pharmaceuticals and nutraceuticals. With applications in drug delivery and care solutions, it is employed orally, rectally, and topically. Ideal for pharmaceutical manufacturing, it contributes to API manufacturing, excipients, and coatings. Available in a liquid form, Kollisolv® PEG 300 plays a crucial role in enhancing the efficacy and formulation flexibility in the healthcare and pharma industry.

MASCEROL™ Glycerine 99.7 USP, non-GMO, RSPO MB is highly refined with a minimum glycerol content of 99.7%. MASCEROL™ Refined Glycerine is used as a base ingredient in personal care preparations. It provides moisturizing properties and improves skin permeability. It is a gentle ingredient for anti-aging and anti-irritant cosmetics found in skin and hair care applications, shaving cream, soaps, and water-based lubricants. MASCEROL™ Refined Glycerine is used as an excipient in pharmaceutical production and preparations for improving smoothness, providing lubrication, and because of its humectant characteristics. It is also found in allergen immunotherapies, cough syrups, tinctures, elixirs, and expectorants. It is a tablet-holding agent and a key ingredient in soft gelatin capsules. In food as well as beverage applications, MASCEROL™ serves as a humectant or wetting agent, solvent, sweetener, or sugar substitute (approximately 60% as sweet as sucrose), thickening agent, or filler.

MASCEROL™ Glycerine 99.7 USP, non-GMO is highly refined with a minimum glycerol content of 99,7%. MASCEROL™ Refined Glycerine is used as a base ingredient in personal care preparations. It provides moisturizing properties and improves skin permeability. It is a gentle ingredient for anti-aging and anti-irritant cosmetics, found in skin & hair care applications, shaving cream, soaps & water-based lubricants. MASCEROL™ Refined Glycerine is used as an excipient in pharmaceutical production and preparations for improving smoothness, providing lubrication, and because of its humectant characteristics. It is found in allergen immunotherapies, cough syrups, tinctures, elixirs & expectorants. It is a tablet-holding agent and a key ingredient in soft gelatin capsules. In food as well as beverage applications MASCEROL™ serves as a humectant or wetting agent, solvent, sweetener or sugar substitute (approx. 60 % as sweet as sucrose), thickening agent, or filler.

Galaxy™ 789 SP-MB, an anionic surfactant in needle form, minimizes dusting while boasting excellent foaming power, detergency, and emulsification capabilities. Trusted across industries, it finds application in toothpaste as a foaming agent and in pharmaceuticals as an emulsifier. With its multifunctional properties, Galaxy™ 789 SP-MB ensures optimal performance in various formulations.

BIOGRUND’s ready-to-use printing ink BonuPrint® is a fine, homogenous, liquid pigment dispersion for solid oral dosage forms, available as an organic or aqueous solution.

Mannitol

D-Mannose 99%

PHARMACOAT® 645 is a binder, it does not interact with drugs. It has superior stability, a non-ionic character and is widely used as a binder for granulation. Due to its plant derived nature and excellent moisture stability, PHARMACOAT®® replaces gelatin in hard capsule manufacturing. It is easy to use as a film coating material that provides an excellent finish . It is also used as taste making agent for bitter tasting drugs.

PHARMACOAT® 615 is easy to use film coating material that provides an excellent finish. It is also used as taste making agent for bitter tasting drugs.

PHARMACOAT® 603 is effective as a binder, since it does not interact with drugs. It has superior stability, a non-ionic character and is widely used as a binder for granulation. It is easy to use it as a film coating material that provides an excellent finish

PHARMACOAT® 606 is a binder, it does not interact with drugs. It has superior stability, a non-ionic character and is widely used as a binder for granulation. Due to its plant derived nature and excellent moisture stability, PHARMACOAT®® replaces gelatin in hard capsule manufacturing. It is also used as taste making agent for bitter tasting drugs.

TYLOPUR® 645 is a versatile hypromellose, compliant with USP, JP, EP. It is a film coating material that provides an excellent finish.It is a effective binder, it does not interact with drugs.It also enhances the solubility of poorly solule APIs.

L-HPC (low-substituted hydroxypropyl cellulose NF, JP, EP) This dual functioning excipient acts as both a disintegrant and binder. It is not the same as HPC. L-HPC is insoluble in water. It is an effective disintegrant due to its swelling action in water. Because is has good compressibility, it functions as a dry binder.L-HPC benefits are:Enhanced stability because it is non-ionic and has low water activityIt is peroxide free and provides excellent compatibility for oxygen sensitive APIsImproved disintegrationA variety of grades are available depending on the application.L-HPC LH-11 is suitable for direct compression and prevents capping during compression.

TYLOPUR® 615 is a versatile hypromellose, compliant with USP, JP, EP. It is a film coating material that provides an excellent finish.It is a effective binder, it does not interact with drugs. It is an excellent taste making agent for bitter tasting drugs.

Shin-Etsu AQOAT® AS-HG-Hypromellose acetate succinate (HPMCAS, NF, JP) is an enteric coating material that can be used in aqueous or organic media.It is also used as solubility enhancement of poorly soluble APIs.

HPMCP is a monophthalic acid ester of hypromellose.HP-50 is enteric coating agent soluble at lower pH

Amorphous solid dispersion is a technology for solubility enhancement of drugs.Shin-Etsu AQOAT® AS-LMP is used as solubility enhancement of poorly soluble APIs.

Shin-Etsu AQOAT® AS-LG -Hypromellose acetate succinate (HPMCAS, NF, JP) is an enteric coating material that can be used in aqueous or organic media.It is also used as solubility enhancement of poorly soluble APIs.

Shin-Etsu AQOAT® AS-LF -Hypromellose acetate succinate (HPMCAS, NF, JP) is an enteric coating material that can be used in aqueous or organic media.It is also used as solubility enhancement of poorly soluble APIs.

L-HPC (low-substituted hydroxypropyl cellulose NF, JP, EP) This dual functioning excipient acts as both a disintegrant and binder. It is not the same as HPC. L-HPC is insoluble in water. It is an effective disintegrant due to its swelling action in water. Because is has good compressibility, it functions as a dry binder.L-HPC benefits are:Enhanced stability because it is non-ionic and has low water activityIt is peroxide free and provides excellent compatibility for oxygen sensitive APIsImproved disintegrationA variety of grades are available depending on the application.L-HPC LH-22 is suitable for direct compression.

L-HPC (low-substituted hydroxypropyl cellulose NF, JP, EP) This dual functioning excipient acts as both a disintegrant and binder. It is not the same as HPC. L-HPC is insoluble in water. It is an effective disintegrant due to its swelling action in water. Because is has good compressibility, it functions as a dry binder.L-HPC benefits are:Enhanced stability because it is non-ionic and has low water activityIt is peroxide free and provides excellent compatibility for oxygen sensitive APIsImproved disintegrationA variety of grades are available depending on the application. L-HPC LH-32 is suitable for wet granulation, pellet extrusion and layering.

Shin-Etsu AQOAT® AS-HF-Hypromellose acetate succinate (HPMCAS, NF, JP) is an enteric coating material that can be used in aqueous or organic media. It is also used as solubility enhancement of poorly soluble APIs.

Amorphous solid dispersion is a technology for solubility enhancement of drugs.Shin-Etsu AQOAT® AS-MMP is used as solubility enhancement of poorly soluble APIs.

HPMCP is a monophthalic acid ester of hypromellose.HP-55S is enteric coating agent with greater strength and higher acid resistance due to its high molecular weight

Shin-Etsu AQOAT® AS-MF -Hypromellose acetate succinate (HPMCAS, NF, JP) is an enteric coating material that can be used in aqueous or organic media.It is also used as solubility enhancement of poorly soluble APIs.

L-HPC (low-substituted hydroxypropyl cellulose NF, JP, EP) This dual functioning excipient acts as both a disintegrant and binder. It is not the same as HPC. L-HPC is insoluble in water. It is an effective disintegrant due to its swelling action in water. Because is has good compressibility, it functions as a dry binder.L-HPC benefits are:Enhanced stability because it is non-ionic and has low water activityIt is peroxide free and provides excellent compatibility for oxygen sensitive APIsImproved disintegrationA variety of grades are available depending on the application.L-HPC LH-21 is suitable for wet granulation.

Amorphous solid dispersion is a technology for solubility enhancement of drugs. Shin-Etsu AQOAT® AS-HMP is used as solubility enhancement of poorly soluble APIs.

L-HPC (low-substituted hydroxypropyl cellulose NF, JP, EP) This dual functioning excipient acts as both a disintegrant and binder. It is not the same as HPC. L-HPC is insoluble in water. It is an effective disintegrant due to its swelling action in water. Because is has good compressibility, it functions as a dry binder.L-HPC benefits are:Enhanced stability because it is non-ionic and has low water activityIt is peroxide free and provides excellent compatibility for oxygen sensitive APIsImproved disintegrationA variety of grades are available depending on the application. L-HPC LH-31 is suitable for wet granulation, pellet extrusion and layering.

HPMCP is a monophthalic acid ester of hypromellose.HP-55 is a regular grade enteric coating agent.

Shin-Etsu AQOAT® AS-MG -Hypromellose acetate succinate (HPMCAS, NF, JP) is an enteric coating material that can be used in aqueous or organic media.It is also used as solubility enhancement of poorly soluble APIs.

BIOGRUND’s one-step binding agent CompactCel® provides an easy to use, granulated and homogeneous compound of PVP/NaCMC or HPC/ NaCMC, which acts as a perfect dry binder.

AquaPolish® SR creates a strong and insoluble film coating with good adhesion, through which the active ingredient diffuses. The use of highquality, insoluble cellulose ethers or Ammonio Methacrylate Copolymer (Type A, Type B) in combination with soluble cellulose ethers, plasticizing and coloring additives, guarantees film coatings that are always reproducible. By varying the type and amount of the cellulose ethers used, a wide range of release profiles can be achieved.

BonuCel® provides easy-to-use cellulose ethers for pharmaceutical and nutritional products. The main application of Hypromellose is film coating. The fine, homogeneous blends of selected high quality cellulose ether polymers provide excellent film forming properties and sustained release profiles. A wide range of standard viscosities is offered to deal with different application requirements. Additionally, BIOGRUND offers an exclusive service by finely adjusting viscosities.