Products in Pharmaceutical Actives & Precursors: Anti-Cancer Agent

Paclitaxel is a pure molecule obtained from the twig and leaves of Taxus x media Rehder. This product is used as an anticancer and antimitotic active pharmaceutical ingredient (API) in the pharmaceutical industry, with more than 97% of the active component by HPLC. This product has been granted a Certificate of Suitability (CEP).

Indena Cabazitaxel is a pure molecule obtained from the twigs and leaves of Taxus baccata L. This product is used as an anticancer and antimitotic API in the pharmaceutical industry. It has more than 97.5% active content, as determined using HPLC.

Paclitaxel S is a pure molecule obtained from the twig and leaves of Taxus baccata L. This product is used as an anticancer and antimitotic API in the pharmaceutical industry, with more than 97% of the active component by HPLC. It has been granted a CEP.

Docetaxel is a pure molecule obtained from the twigs and leaves of Taxus baccata L. This product is used as an anticancer and antimitotic API in the pharmaceutical industry. It has an active content of more than 97%, as determined by HPLC.

Docetaxel Trihydrate is a pure molecule obtained from the twigs and leaves of Taxus baccata L. This product is used as an anticancer and antimitotic in the pharmaceutical industry. It has an active content of more than 97.5%, as determined by HPLC.

Amino acid-like antineoplastic agent and chemotherapy medication used to treat multiple myeloma, ovarian cancer, melanoma, and AL amyloidosis.

DEP® docetaxel is water-soluble and does not require surfactant such as polysorbate 80 for dissolution. Drug substance is readily manufactured at scale using standard chemistry under cGMP.

Alfa Chemistry Materials Lenalidomide is a light yellow powder with the chemical name 3-(4-amino-1-oxoisoindolin-2-yl)piperidine-2,6-dione which is freely soluble in N methylpyrrolidone and soluble in N,N-dimethylformamide or dimethyl sulfoxide. Lenalidomide is used to treat various types of cancers. It works by slowing or stopping the growth of cancer cells. It is also used to treat anemia in patients with certain blood/bone marrow disorders (myelodysplastic syndromes-MDS).

DEP® irinotecan is a novel, patented nanoparticle formulation of SN-38, the active metabolite of irinotecan, delivered using Starpharma’s proprietary DEP® technology. DEP® irinotecan has shown a number of benefits compared to the original form of irinotecan, including significant improvements in anti-cancer efficacy and improved survival in multiple human cancer models. DEP® irinotecan is the third DEP® product to enter the clinic from Starpharma’s internal portfolio.

Pazopanib is a multiple kinase inhibitor that limits tumor growth by targeting angiogenesis via inhibition of enzymes including vascular endothelial growth factor receptor (VEGFR), platelet-derived growth factor receptor, useful for treating Renal cell carcinoma

Alfa Chemistry Materials Tamoxifen is an estrogen receptor antagonist and partial agonist which has been shown to induce apoptosis in human malignant glioma cells and to block VEGF production in breast cancer cells.

Qingdao Qingmei Biotech Imatinib mesylate is used in the treatment of chronic myelogenous leukemia (CML) rapidly varied period, accelerating period or alpha interferon treatment failure after chronic-phase, Not on surgical resection or metastatic malignant gastrointestinal stromal tumor (GIST) patients.

DEP® cabazitaxel is Starpharma’s detergent-free version of cancer drug, Jevtana®, which is marketed by Sanofi Aventis to treat advanced prostate cancer, and is also under clinical development for a range of other cancer types, including testicular, ovarian, breast, bladder, and head and neck.