Brands in Modified & Controlled Release

BASF offers the widest range of IPEC-GMP lipid-based excipients, suitable for topical  and oral drug formulations. We are committed to providing high quality products supported  by best-in-class Regulatory, Quality, and Technical teams. We value sustainability and are  the first major supplier to offer 100% RSPO certified lipid-based excipients. The Kolliwax® product line is an extensive portfolio of structuring agents that provide formulation stability.  These excipients can be used in the development of numerous oral and topical dosage forms.

Kollidon® grades are processed via melt granulation, spray drying, and HME, these materials are suitable for a variety of formulations. Whether the target formulation is a tablet or transdermal patch, the Kollidon® family of multifunctional excipients is ready to resolve any formulation challenge. Kollidon® excipients come in various grades, giving you the flexibility to tailor your formulation based on your individual needs.

TYLOPUR® is a versatile hypromellose, compliant with USP, JP, EP. The low viscosity grades are especially suitable for the design of film-coated tablet formulations. In addition, TYLOPUR® is effective as a binder, since it does not interact with drugs. It has superior stability, a non-ionic character and is widely used as a binder for granulation. Due to its plant derived nature and excellent moisture stability, TYLOPUR® replaces gelatin in hard capsule manufacturing.

Kollicoat® polymers can also be used for taste masking to improve patient compliance. While these excipients are predominantly used for oral applications, coating polymers can also be utilized for the development of topical films and transdermal patches as film and matrix formers, respectively. The Kollicoat® family of coating polymers consists of a broad range of chemistries to address various film coating challenges.

The unique cocoa powders of JS are highly defatted and near 100% fiber solids. Applied in bakery and confectionery, ice cream and dairy as well as in low caloric health products. Ensuring high intense coloring and dispersibility in liquid is exceptionally good. Due to less fat, a mild alkalization still results in a strong intrinsic color impact without requirements to label alkali (under 7%). 

Shin-Etsu Chemical Co., Ltd. began to produce water soluble cellulose ethers in 1962, with the trade name METOLOSE®. METOLOSE® consists of Methylcellulose (methylcellulose USP) and three substitution types of Hydroxypropylmethylcellulose (Hypromellose USP) each available in several grades differing in viscosity. METOLOSE® can be used as a binder for solid dosage forms such as tablets and granules. It also provides a variety of functions such as water retention, thickening, protective colloid, surface activity, etc. It also can be used as a hydrophilic matrix agent. The hydrophilic matrix system is the simplest sustained release technology for oral dosage forms, consisting essentially of a drug and a water soluble highly viscous polymer. Recent advances in this hydrophilic matrix system have allowed more controllable and reproducible drug release by controlling the chemical and physical properties of the polymer. METOLOSE® SR is especially suitable for this application, and provides a genuine consistency in the final products.

TYLOPUR Xtend Nutra® is a plant derived ingredient (high viscous hydroxypropyl methylcellulose, HPMC) that has been developed by Shin-Etsu to provide a controlled, extended release of active compounds over a longer period of time, prolonging their effects on human body. TYLOPUR Xtend Nutra® acts as a hydrophilic matrix agent in hydrophilic matrix system, which is the simplest sustained release technology, consisting essentially of an active compound and a water soluble highly viscous natural polymer. Such a system allows a simple and straight forward direct compression formulation and a reduction of doses per day. It is not only cost effective but it is also consumer friendly. The mechanism of action of TYLOPUR Xtend Nutra® in hydrophilic matrix tablets consists of initial swelling caused by the hydration of a tablet, protective gel formation, which regulates the degree of active compound’s release, and time-related extended release of an active compound through the gel layer.

Hydro~Kote hydrogenated vegetable oils are refined, bleached, and deodorized. Their unique properties make them very useful in a variety of applications for the pharmaceutical industry. Their Applications Include: Topical creams and ointments, Suppositories, Controlled Release, Replacement to cocoa butter

Acconon products are well-characterized mixtures of polyoxyethylene mono- and diglycerides, fatty acids or fatty alcohols. In addition to functioning as excellent oil/water emulsifiers, many of these products can add emolliency to creams and lotions. Our line includes alkoxylates based on natural oils such as coconut, castor, and apricot oil.

Captex® Medium-Chain Triglycerides originate from renewable vegetable-based sources (typically palm, palm kernel and/or coconut). These food-grade, safe, responsibly sourced ingredients are best known for their functional benefits as emulsifiers, solubilizers and refatting agents for use in a range of markets and applications including, personal care, cosmetics, food, and nutritional supplements. Additionally, these products boast numerous health benefits in areas such as weight management, energy, and cognition.ABITEC offers a variety of C8 (caprylic) and C10 (capric) variations to suite your formulation requirements.

CAPMUL® multi-functional, high purity monoesters provide superior skin penetration and emolliency with excellent effects against microorganisms. Certain grades of CAPMUL® may be used to inhibit the growth of gram positive and negative bacteria, yeast, and mold in many "preservative free" products. They are used to produce stable emulsions, to modify viscosity and they can act as carriers and vehicles in selected applications.

PEARLITOL® Flash Co-processed mannitol starch provides excipient functional properties of filler/binder as well as some disintegrant benefit to your orally dispersable tablets. PEARLITOL® Flash offers excellent chemical inertness, consistent rapid disintegration whatever the compression force making tablet formulation surprisingly simple. It is a compound of mannitol and starch adapted to direct compression formulation. PEARLITOL® Flash can be used in various oral dosage forms in both pharmaceutical and nutraceutical applications including fast disintegrating tablets and orally dispersible tablets.

KLEPTOSE® Beta-cyclodextrins are efficient solubilizers, stabilization enhancers and taste-masking agents. A full range is available for use in many dosage forms, from solid to liquid. Molecular encapsulation with beta-cyclodextrins is an accepted and useful tool for pharmaceutical formulators, with many pharmaceutical products containing cyclodextrin complexes on the market. Roquette has developed a wide range of KLEPTOSE® offering features like low water content, various particle size and directly compressible properties with KLEPTOSE® DC. Roquette has pioneered the industrial development of cyclodextrins with its KLEPTOSE® range of beta-cyclodextrins. KLEPTOSE® can be used in various oral dosage forms in both pharmaceutical and nutraceutical applications including swallowable tablets, chewable tablets, effervescent tablets, lozenges, hard capsules, soft capsules, orally dissolving films, blends, granules, pellets premix, medicated confectionary, syrups, suspensions and liquids.

PhytoChol® ensures a dependable supply of synthetic cholesterol. Tailored for injectable drug delivery and biopharmaceutical cell culture, Evonik offers two specialized grades. These grades meet the distinct requirements of each application, providing a secure and stable source for pharmaceutical and biopharmaceutical needs. With PhytoChol®, Evonik delivers a versatile solution for applications demanding synthetic cholesterol, ensuring reliability and adherence to specific industry standards.

The standard LACTEL® portfolio boasts of a broad catalog of standard polymers available as a cost effective supply due to streamlined manufacturing processes. Common application areas for LACTEL® standard polymers include veterinary medicine, where bioresorbable polymers are used in long-acting injectable formulations, and human generic drug formulations, which require price-sensitive planning and quick shipment to support demanding, fast-paced markets.

The RESOMER® standard catalog of parenteral excipients includes Poly (lactide) and Poly (lactide-co-glycolide) polymers with a variety of high and low molecular weights and polymer compositions which can be selected to help tune degradation times over durations of up to 18 months. RESOMER® polymers are solvent-purified to achieve lower residual monomer levels, and the portfolio includes a selection of customizable options.