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Aversion Technologies Denatonium Saccharide is the most bitter substances known, judged to be 5 times more bitter than denatonium benzoate. Detectable at as little as a few parts per billion, this compound will make a product so bitter that children and pets will not be able to swallow it. Denatonium saccharide makes sweet but highly toxic products such as antifreeze and detergents taste foul. Research shows that people can detect denatonium saccharide in water at 50 parts per billion. Denatonium saccharide is bitter at 1 to 10 ppm, at 30 to 100 ppm virtually any product becomes impossible to masticate. Denatonium saccharide is also stable and inert. In addition, so little is needed that the properties of the product remain unchanged.