BioCell Collagen - CG - BIOCELL TECHNOLOGY

Knowde Enhanced TDS

Identification & Functionality

INCI Name: Hydrolyzed Chicken Cartilage Extract
Cosmetic Ingredients Functions: Anti-Aging Agent,
Humectant,
Moisturizing Agent,
Protective Agent
Technologies: Cosmetic Ingredients
Product Families: Cosmetic Ingredients — Cosmetic Actives
Skin Actives
Cosmetic Ingredients — Functionals
Other Functional Additives

Features & Benefits

Benefit Claims: Anti-Aging,
Anti-Irritant,
Collagen Boosting,
Fine Lines Reduction,
Humectancy,
Hydrating,
Improves Skin Elasticity,
Moisturizing,
Promotes Youthful Skin,
Suppleness,
Volumizing
Labeling Claims: Allergen-free,
Dairy-free,
Gluten-free,
Non-GMO,
Non-Irritant,
Non-Toxic,
Oil-free,
Organic,
Soy-free,
Sugar-free
Product Properties: BioCell Collagen® has strong hyaluronidase inhibition

BioCell Collagen® protects HA from degradation

BioCell Collagen® provides collagen peptides and hyaluronic acid.

HA level in the skin is maintained by the balance of HA synthases and hyaluronidases. Aging is associated with heightened hyaluronidase activity which accelerates HA breakdown contributing to skin aging process.
Dermatologist Reviewed: Non-Irritating

Allergy Tested

Non-Cytotoxic

Applications & Uses

Markets: Personal Care
Applications: Personal Care — Beauty & Care
Skin Care
Skin Care Applications: Anti-Aging Products,
Moisturizers
Cosmetic Applications: Anti-Aging Cosmetic Products

Moisturizing Cosmetic Products

Oil-Free Hydrating Cosmetic Products
Usage: Formulators and manufacturers of cosmetics.
Applications: BioCell Collagen® CG should be processed below 40 °C and is incorporated into the aqueous phase of a cosmetic formulation.

Properties

	Value	Units	Test Method / Conditions
pH Value (55°C)	3.7 - 4.5	—	—

Technical Details & Test Data

Research Data: 1. Toxicology and allergenicity studies Our early studies showed that BioCell Collagen CG-WS was hypoallergenic on the human skin and did not have cytotoxicity on the cells tested.

2. Hyaluronidase inhibition study

What is unique with BioCell Collagen is its inhibitory activity of hyaluronidase. HA is present in virtually all tissues and bodily fluids while one third of HA is turned over daily by coordinated action of HA synthases and hyaluronidases. Our study showed that hyaluronidase was specifically inhibited by BioCell Collagen in a dose-dependent fashion.

Given that hyaluronidase-mediated degradation of HA is implicated in various aging-associated physiological conditions, BioCell Collagen’s property of inhibiting hyaluronidase may have a profound implication especially in terms of aging processes which takes place in the joint and the skin. This data suggested that BioCell Collagen had multiple biological properties in addition to replenishment of structural loss of collagen and HA in aging skin that can be harnessed to maintain the integrity and amount of HA for younger-looking skin.

Packaging & Availability

Storage & Handling