Knowde Enhanced TDS
Identification & Functionality
- Chemical Family
- Protein Type
- Food Ingredients Functions
- Pharma & Nutraceuticals Functions
- Product Families
- Composition
The patented ingredient DNF-10® is an active fraction obtained after protein hydrolysis of Saccharomyces cerevisiae, a yeast species used for thousands of years in baking, fermented food and beverage manufacturing processes. The manufacturing of DNF-10® involves enzymatic proteolysis and a selection of peptides with a molecular weight <10kDa after an ultrafiltration step. The material is then spray-dried to obtain a dried powder.
Features & Benefits
- Product Highlights
- Selected peptidic fraction from Saccharomyces cerevisiae
- Clinically proven benefits on a total of 135 subjects
- Reduction of caloric intake significant after the first weeks (down to -600kcal/day after 8 weeks)
- Significant weight loss after the first month
- Weight loss is from fat mass reduction
- Abdominal fat and waist circumference significantly decrease
- Water-soluble and heat-resistant; suitable for supplements and functional foods
Applications & Uses
- Applications
- Dosage Form
- Use Level
- 500
- Mechanism of Action
DNF-10® decreasing food intake :
A significant action on the modulators of short-term food intake at the hypothalamic level (NPY) and at the digestive level with a reduction in the hunger hormone ghrelin have been demonstrated.
Over the longer-term, DNF-10® also regulates our cellular secretion of leptin, the satiety hormone.
Technical Details & Test Data
- Clinical Studies
DNF-10® benefits have been studied in several clinical studies on a total of 135 subjects involving different delivery systems.