Knowde Enhanced TDS
Identification & Functionality
- Chemical Family
- Ingredient Origin
- Cosmetic Ingredients Functions
- Technologies
- Product Families
Features & Benefits
- Benefit Claims
- Labeling Claims
- Product Benefits
- Decrease cortisol level on keratinocytes
- Increase Hyaluronic acid synthesis by 47%
- Increase Collagen III synthesis by 73%
- Increase Elastin synthesis by 74%
- Product Pathway
Inhibits the conversion of Cortisone to Cortisol by blocking 11Beta-HSD1 on skin and scalp.
Applications & Uses
- Markets
- Color Cosmetic Applications
- Skin Care Applications
Technical Details & Test Data
- Efficacy Studies
- Directly inhibits the cortisone-to-cortisol converting enzyme: 11β-hydroxysteroid dehydrogenase 1
- Decrease cortisol in keratinocytes by 43%
- Increase hyaluronic acid synthesis by 47%
- Increase collagen III synthesis by 73% in presence of UVB (ex vivo)
- Increase elastin synthesis by 74% in presence of UVB (ex vivo)
- Suggested Association
- Primadulcine + Hinoline for acne-prone skin: bacterial control and sebum reduction.
- Primadulcine + Dumaflorine to have both preventing and repairing anti-aging effects.