Knowde Enhanced TDS
Identification & Functionality
- Active Component
- Ingredient Name
- Ingredient Origin
- Pharma & Nutraceuticals Functions
- Product Families
- Plant Source
Resin
Features & Benefits
- Benefit Claims (Health)
- Labeling Claims
- Food Ingredients Features
- CASPEROME® Features
CASPEROME®, highly standardized in boswellic acids is formulated with Phytosome® technology to achieve optimized absorption.
- CASPEROME® has been shown to support muscoskeletal health. Furthermore, in combination with sodium hyaluronate, collagene and glucosamine, has been shown to be supportive against elbow and tendon challenges
- CASPEROME® has been shown to support gut health, significantly alleviating the most common gut discomforts, compared to the best available managements.
Furthermore in literature is is reported that:
- KBA and AKBA are selective 5-lipoxygenase inhibitor and then capable to manage the inflammatory response function through leukotriene inhibition. Recent findings have shifted the focus on β-boswellic acid, the major triterpenoid from the gum-resin, and its capability to modulate the inflammatory response enzymes cathepsin (catG) and microsomal prostglandin E synthase (mPGES)-1, suggesting that β-boswellic acid plays a major role while the whole bouquet of triterpenoid acids is important for the beneficial effects of boswellia
- Boswellia extracts have been demonstrated to be useful for bowel related inflammatory responses, and to improve physical function in subjects with joint and tendon challenges.
The bioavailability of boswellic acids from CASPEROME® is greatly optimized both at the plasma and at the tissue level.
- CASPEROME® Benefits
With Casperome®, the whole variety of boswellic acids reaches multiple targets providing a pleiotropic effect form muscles to the gut, stimulating a healthy inflammatory response. Moreover, thanks to its exclusive Phytosome® formulation, Casperome® shows an optimized distribution since the first administration.
Muskoskeletal Health
Casperome® supports musculoskeletal health reducing stress and inflammatory status of joints and muscles of actual athletes. An example? It can help to heal from ankle sprains and relieve knee joint from stress.
Gut Health
Recent human studies have focused on the possible role of Casperome® in the management of subjects with gastrointestinal issues like acute diarrhea and new human evidence confirms the benefits in reducing discomforts and promoting a faster normalization of the gut health status.
Respiratory Health
An add-on administration of Casperome® is beneficial for people with asthma as it helps reduce the need for inhalation therapy with ICS + LABA.
- Health Benefits
Gut health, Joint health, Muscoskeletal health, Respiratory health
Applications & Uses
- Markets
- Food & Nutrition Applications
- Use Level
- 250 - 500 mg/day
Properties
- Physical Form
- Appearance
- Yellow powder
- Assay
| Value | Units | Test Method / Conditions | |
| Boswellic Acids | min. 25.0 | % | HPLC Method |
Technical Details & Test Data
- Scientific Evidence
- The gastrointestinal health challenge is solved! The newest evidence highlights that Casperome® plays a key role in supporting gastrointestinal health, adding another important piece to its potential.
- In the summer, traveling abroad is the perfect chance to taste new food, but new culinary experiences may often put at risk people’s gut health. Gut health already is a relevant issue all over the world. Just to give an idea, in the USA from 60 to 70 million people are affected by all digestive diseases, over 1 million residents in the USA and 2.5 million in Europe are estimated to have Inflammatory Bowel Disease and Irritable Bowel Syndrome occurs in up to 15% of the United States population.
- The latest study has proven that the optimized Boswellia extract can normalize intestinal motility, thus counteracting the formation of loose and watery stools: in conditions when the risk of experiencing acute diarrhea may be higher, it significantly reduces the number of stools and duration of motility unbalance, along with associated secondary conditions.
- Casperome® into Action
- Several scientific evidence have shown Casperome® real potential in reducing musculoskeletal stress, promoting respiratory health and fighting gut inflammation, but how does it work? Mechanistic studies have proven that the boswellic acids can act as a Ca2+ channels modulators and, thanks to the Phytosome® delivery system, they can easily and effectively reach their intestinal smooth muscles cells, their final target.
- Moreover, the literature reports that Boswellia extracts are effective in the management of various inflammatory response functions through the interaction with actors of the inflammatory chains such as of lipoxygenases (responsible for the synthesis of leukotrienes), proteases (cathepsin G) and nuclear factor kB (activated in many inflammatory chronic diseases). In addition, BAs reduce the overexpression of alpha tumor necrosis factor (TNF-α) and matrix metallo-proteinases (MMP), which play a role in inflammatory processes.