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Relissa™ is not your typical lemon balm ingredient. It is a standardized extract of Melissa officinalis leaves with a high content of hydroxycinnamic and rosmarinic acid, combined with an innovative formulative technology. The unique combination of high and standardized content of hydroxycinnamic and rosmarinic acid, along with the innovative formulative technology, sets Relissa™ apart from other lemon balm extracts.

Ingredient Name: Lemon Balm Extract

Active Component: Hydroxycinnamic Acid, Rosmarinic Acid

Functions: Phytochemical

Ingredient Origin: Natural Origin, Plant Origin

Labeling Claims: Naturally Derived, Plant-Based, Sustainable

Knowde Enhanced TDS

Identification & Functionality

Ingredient Name
Pharma & Nutraceuticals Functions
Plant Source

Leaves

Features & Benefits

Product Overview
  • High and standardized content of hydroxycinnamic and rosmarinic acid plus an innovative formulative technology: that’s why Relissa™ is not the usual lemon balm extract.
  • The leaves of Melissa officinalis are the starting point of the process, providing the bioactive compounds responsible for the several biological activities (eg: promote sleep, relaxation and calming effect).
  • Furthermore, the ingredient is formulated with phospholipids (lecithins) to allow a better dispersion in gastrointestinal fluids and so improve its bioabsorption profile, optimizing Relissa™ biological performances.
RELISSA™ Features and Benefits
  • RELISSA™ is the new ingredient that embraces all Indena’s milestones: 100 years of scientific background, innovative formulative solutions and attention to the ingredient source. In fact, for RELISSA™ are chosen the best Melissa officinalis extracts (European origin), with an eye to the environmental footprint and sustainability: the goal is to always select the most virtuous suppliers that can guarantee, at the same time, quality and green attitude.
  • The leaves of Melissa officinalis are the starting point of the process, providing the compounds responsible for the several beneficial effects like promoting sleep, relaxation and calming.
  • More than 50 compounds have been identified in the lemon balm extracts, however its positive activity is mostly due to hydroxycinnamic and rosmarinic acids and derivatives that, in RELISSA™, have been quantified and standardized.
  • RELISSA™ is formulated with phospholipids (lecithins) to allow a better dispersion in gastrointestinal fluids, optimizing bioabsorption profile and performances.
  • Lately, there has been an increased interest in how the microbiome may influence our wellbeing, especially in the realm of mood and sleep.
  • Lactobacillus rhamnosus - a bacteria able to colonize the gastrointestinal tract - has been proven able to improve night rest and rapid eye movement (REM) sleep, thanks to a positive influence over short-chain fatty acids (SCFAs) controlling the expression of genes responsible for sleepwake rhythms.
  • RELISSA™ has shown no negative interactions with Lactobacillius rhamnosus, thus safeguarding its beneficial effect.
  • RELISSA™ can also be formulated in gummies, an increasingly popular solution on the market.
Health Benefits

Calming action, Healthy sleep, Relaxation

Applications & Uses

Dosage Form
Food & Nutrition Applications
Use Level
200 - 400 mg/day

Properties

Appearance
Light brown powder
Assay
ValueUnitsTest Method / Conditions
Total Hydroxycinnamic Acids17 - 23%HPLC Method

Technical Details & Test Data

Relissa™ into Action
  • Melissa officinalis has been known for centuries and used for several applications thanks to its calming and “antistress” action, promoting sleep and relaxation.
  • More than 50 compounds have been identified in the lemon balm extract, however its biological activity is mostly due to hydroxycinnamic and rosmarinic acids and derivatives that, in Relissa™, have been quantified and standardized (hydroxycinnamic acids 17-23% by HPLC).
  • Other investigated effect of lemon balm includes antioxidant and spasmolytic activity, neuroprotection and anxiolytic action.
  • Lately, there has been an increased interest in how the microbiome may influence our wellbeing, especially in the realm of mood and sleep. Lactobacillus rhamnosus - a bacteria able to colonize the gastrointestinal tract - has been proven able to improve night rest and rapid eye movement (REM) sleep, thanks to a positive influence over short-chain fatty acids (SCFAs) controlling the expression of genes responsible for sleepwake rhythms.
  • RELISSA™ has shown no negative interactions with Lactobacillius rhamnosus, thus safeguarding its beneficial effect.
  • RELISSA™ can also be formulated in gummies, an increasingly popular solution on the market.