Knowde Enhanced TDS
Identification & Functionality
- Ingredient Name
- Food Ingredients Functions
- Pharma & Nutraceuticals Functions
Features & Benefits
- Benefit Claims (Health)
- Food Ingredients Features
- Product Overview
Coenzyme Q10 (CoQ10), also known as ubiquinone or ubidecarenone, is a key endogenous factor in cell energy production. It has shown protective properties against oxidative stress, mainly in skeletal and heart muscles and, more recently, at the endothelial level.
Cardiovascular Oxidative Stress Protection
- Endothelial function is an important early marker for cardiovascular risk, reflecting the ability of the endothelial layer to fight early pro-atherosclerosis conditions. Since endothelial dysfunction is primarily driven by ROS and NO deficiency, the antioxidant potential of Ubiqsome® could be a valuable ally to maintain the endothelium in good health. s beyond any other available on the market.
- A recently published study on healthy young people has confirmed this hypothesis, showing an improvement of endothelial function in both acute and chronic settings after the administration of Ubiqsome®.
Muscular Oxidative Stress Protection
Reactive oxygen species (ROS) are overproduced during intense training and exercise, contributing to muscular stress and damage. A study on healthy, aging runners showed that the administration of Ubiqsome® optimizes plasmatic and muscular CoQ10 concentration, counteracting oxidative stress right where it’s needed.
- UBIQSOME® Features and Benefits
UBIQSOME® is the first and only CoQ10 formulation on the market to have been tracked down from oral administration to its real and sole target: the inner space of cells, where it is needed.
UBIQSOME® is also the only patent pending CoQ10 formulation to benefit from Phytosome® technology, for an optimized bioabsorption of the cofactor:
- in the pk studies, UBIQSOME®has been shown to significantly optimize CoQ10 plasmatic levels in a dose dependant fashion and to show 14-fold higher solubility in intestinal simulated fluids
- in the human study on over-50s healthy athletes performing a complete training session in a climatic chamber, UBIQSOME® has been shown to significantly optimize CoQ10 levels in plasma
- for the 1st time in humans, the optimization of CoQ10 levels in muscolar cells has been demonstrated with two different analytical methods: +37% by HPLC and +60% by immunofluorescence
- moreover, a recent human study has also shown promising results, opening new possibilities for cardiovascular wellbeing: UBIQSOME® could optimize the endothelial function (+7%) while reducing the oxidative stress (-27%).
UBIQSOME® can be a cost-effective solution thanks to:
- lower CoQ10 content
- optimized bioabsorption without relying upon expensive capsulating technologies (like softgel)
- industrial-scalable & versatile finished oral dosage forms.
- Health Benefits
Anti-aging, Antioxidant protection, Cardiovascular Health, Cellular energy support, Heart health, Support intensive exercise
Applications & Uses
- Applications
- Food & Nutrition Applications
- Use Level
- max. 500 mg/day
Properties
- Appearance
- Brown yellow powder
- Assay
| Value | Units | Test Method / Conditions | |
| Coenzyme Q10 | 18 - 22 | % | HPLC Method |
Technical Details & Test Data
- Scientific Evidence
A Natural Ally for Cardiovascular Health
- A human study on endothelial protection confirms Ubiqsome®’s potential for cardiovascular health.
- When oxidative stress is an issue, Ubiqsome® is the answer. The latest clinical evidence shows that Ubiqsome® could fight oxidation also at endothelial level, where it may greatly contribute to the wellbeing of the cardiovascular system. Both acute and chronic supplementation with Ubiqsome® are effective in optimizing plasmatic TAC (total antioxidative capacity) and endothelial reactivity.
- Ubiqsome® into Action
- Ubiqsome® confers antioxidant protection for the management of certain health challenges, also tied to aging.
- It is a food-grade bioavailable form of coenzyme Q10 that guarantees significant physiological CoQ10 plasma levels after a single dose and after 2 weeks of treatment.
- It fights oxidation from the inside thanks to its unique properties: Ubiqsome® increases CoQ10 in innermost cellular environments, such as mitochondria, as shown by a recent in-vitro study.
- Furthermore, a dose-related profile is observed and administration is well tolerated.