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Escent

INNOVAD NV/SA Brand

Supplier:INNOVAD NV/SA
Products:2
Escent® is a scientifically proven technology and a unique mycotoxin assessment service. Escent® offers a multifunctional approach to counteract stress in the context of toxic contaminants and guarantee high performance in today’s challenging production conditions. Together with Escent®, Innovad® provides the possibility of discovering the real exposure to mycotoxins through the analysis of mycotoxins in blood, creating a unique platform to effectively mitigate mycotoxin exposure.
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Escent® L banner
INNOVAD NV/SA company logo
Escent® L
  • Functions:Toxin Binder
  • Labeling Claims:Organic
  • Physical Form:Liquid
  • Features:Liver Detoxification, Anti-Stress, Diuretic Effect, Prevents Oxidative Stress, Improves Gut Microflora
Escent® L is an innovative liquid anti-stress solution for mycotoxin control and animal revitalization and combines yeast extracts, yeast fermentation products (Saccharomyces cervisiae) with bioactive contents, chelators, energy sources, minerals, botanicals and organic acids. It ensures a critical supply of nutrients and supportive molecules to counteract the negative impact of feed refusal on metabolism and microflora.
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Escent® S banner
INNOVAD NV/SA company logo
Escent® S
  • Functions:Toxin Binder
  • Physical Form:Solid
  • Features:Improve Liver Function, Prevents Oxidative Stress, Improves Immunity, Reduces Mortality
Escent® S is a stress-related Mycotoxin combat.
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Knowde Brand Highlights

Background Information

Large multi-mycotoxin occurrence

Animals are continuously exposed to many mycotoxins at the same time.

  • 100% exposed to mycotoxins
  • 97% exposed to two or more mycotoxins
  • 50% exposed to 6 or more mycotoxins

Figure 1. Distribution of total number of mycotoxins per case.

Large Presence of Emerging Mycotoxins in Swine

The emerging mycotoxins were the predominant ones in the blood from swine (table 1). Emerging mycotoxins can be as toxic as the legislated mycotoxins (aflatoxins, deoxynivalenol, fumonisins, ochratoxin A, T-2 and zearalenone).

Mycotoxin Prevalence (%)
Tenuazonic acid 68
Enniatin B1 62
Enniatin B 54
Ochratoxin A 54
Beauvericin 30

Table 1. The five most common mycotoxins detected in blood in the introductory global survey in swine farms.

The following reduces the immune response and animal performance:

  • Intestinal toxicity: Enniatins, Beauvericin, and Tenuazonic acid
  • Bloody diarrhoea: Tenuazonic acid
  • Reproductive alterations: Enniatins, Beauvericin, Alternariol, and Alternariol monomethyl ether

Large Presence of Emerging Mycotoxins in Poultry

The emerging mycotoxins were the predominant ones in the blood from poultry (table 2). Emerging mycotoxins can be as toxic as the legislated mycotoxins (aflatoxins, deoxynivalenol, fumonisins, ochratoxin A, T-2 and zearalenone).

Mycotoxin Prevalence (%)
Tenuazonic acid 66
Enniatin B1 34
Ochratoxin A 32
Beauvericin 27
Zearalenone 24

Table 2. The five most common mycotoxins detected in blood in the introductory global survey in poultry farms.

The following reduces the immune response and animal performance:

  • Egg production altered: Enniatins, Beauvericin, Tenuazonic acid, Alternariol, and Alternariol monomethyl ether
  • Intestinal toxicity: Enniatins, Beauvericin, and Tenuazonic acid
  • Gizzard erosions: Tenuazonic acid

Large Presence of Emerging Mycotoxins in Ruminants

The emerging mycotoxins were the predominant ones in the blood from ruminants (table 3). Emerging mycotoxins can be as toxic as the legislated mycotoxins (aflatoxins, deoxynivalenol, fumonisins, ochratoxin A, T-2 and zearalenone).

Mycotoxin Prevalence (%)
Beauvericin 89
Enniatin B1 78
Enniatin B 78
Tenuazonic acid 67
Enniatin A1 34

Table 3. The five most common mycotoxins detected in blood in the introductory global survey in ruminants farms.

The following reduces the immune response and animal performance:

  • Ruminal toxicity: Enniatins, Beauvericin, and Tenuazonic acid
  • Looses feces: Enniatins, Beauvericin, and Tenuazonic acid
  • Reproductive alterations: Enniatins, Beauvericin, Alternariol, and Alternariol monomethyl ether
  • Milk production altered: Enniatins, Beauvericin, Tenuazonic acid, Alternariol, and Alternariol monomethyl ether

The most profound emerging mycotoxins produced by Alternaria and Fusarium species are as follows:

  • Alternaria: Tenuazonic acid, Alternariol, and Alternariol monomethyl ether
  • Fusarium: Enniatins, and Beauvericin
Escent® Multiple Modes of Action

Multiple modes of action to support animal to combat mycotoxin exposure:

  • Binds all kind of toxins

Figure 2. In vitro testing of the binding capacity of Escent® against several mycotoxins at the University of Missouri, USA.

  • Reduces oxidative stress

  • Improves immune response

Fig. a. Improves immune response in Swine.

Fig. b. Improves immune response in Poultry.

Mastitis cases (%)
Control group 20%
Escent® group (27 g/animal/day) 0%

Table.  Improves immune response in Ruminants.

  • Supports the liver and kidneys in swine & poultry

  • Supports the liver and kidneys in ruminants

Detoxification in Pigs

Escent® is the first technology that demonstrated the capacity of reducing mycotoxin levels in the biological fluids under a multi-mycotoxin exposure.

  Detoxification under real farm conditions (studied animals: lactating sows)
  Day 0 (under another mycotoxin binder) Day 30 (Escent® at 1 kg/T for 30 days)
Feed Mycophenolic acid (40 ppb) Aflatoxin B1 (8.1 ppb)
Aflatoxin B2 (1.0 ppb)
Fumonisins (139 ppb)
Ochratoxin A (12.6 ppb)
Blood Alternariol (traces) Fumonisin B3 (detected) Ochratoxin A (traces)
Beauvericin (traces) Ochratoxin A (traces) Tenuazonic acid (traces)
Deoxynivalenol (traces) Tenuazonic acid (1.25 ppb) Zearalenone (Traces)
Fumonisin B1 (25 ppb) Zearalenone (2.52 ppb)  
Fumonisin B2 (12 ppb)    
  Animals suffering respiratory problems (fumonisins), reproductive alterations (alternariol + zearalenone), high mortality. Health status of the animals improved 8 days after Escent® introduction and 30 days later animals did not suffer any clinical symptom.

Escent® reduces levels of mycotoxins in blood and improves health status and performance.

Reduction in biological fluids from piglets: 

  • Deoxynivalenol: - 26%
  • Zearalenone: - 12%

High concentration of mycotoxins in the feed (deoxynivalenol = 900 ppb and zearalenone = 75,000 ppb)

Detoxification in Poultry

Escent® is the first technology that demonstrated the capacity of reducing mycotoxin levels in the biological fluids under a multi-mycotoxin exposure.

  Detoxification under real farm conditions (studied animals: breeders)
  Day 0 (under another mycotoxin binder) Day 30 (Escent® at 1 kg/T for 30 days)
Feed Aflatoxin B1 (4.3 ppb) Aflatoxin B1 (2.7 ppb)
Fumonisins (1,010 ppb) Fumonisins (894 ppb)
Nivalenol (146 ppb) Nivalenol (98.1 ppb)
Zearalenone (150 ppb) Zearalenone (20 ppb)
Blood Alternariol (24.8 ppb) Enniatin B1 (traces) Tenuazonic acid (2.85 ppb)
Alternariol monomethyl ether (3.02 ppb) Tenuazonic acid (3.10 ppb)
Beauvericin (traces) Zearalenone (traces)
  Animals suffering intestinal infections (bacterial and necrotic enteritis). Health status of the animals improved 5 days after Escent® introduction and 30 days later animals did not suffer any clinical symptom.

Escent® reduces levels of mycotoxins in blood and improves health status and performance.

Reduction in blood from broilers: 

  • Deoxynivalenol: - 50%
  • Aflatoxin B1: - 40%

High concentration of mycotoxins in the feed (deoxynivalenol = 5,000 ppb and aflatoxin B1 = 20,000 ppb)

Detoxification in Ruminants

Escent® is the first technology that demonstrated the capacity of reducing mycotoxin levels in the biological fluids under a multi-mycotoxin exposure.

  Detoxification under real farm conditions (studied animals: dairy cows, mid late group)
  Day 0 (under another mycotoxin binder) Day 30 (Escent® at 1 kg/T for 30 days)
TMR Deoxynivalenol (44.2 ppb) Deoxynivalenol (459 ppb)
Fumonisins (682 ppb) Fumonisins (1,320 ppb)
Blood Beauvericin (traces) Enniatin B1 (traces) No mycotoxins detected
Enniatin B (traces) Tenuazonic acid (traces)
  Animals suffering reproductive problem (cystic ovaries) + high number of SCC (>250,000) Reproductive problems solved and reduction of somatic cell counts (<180,000)

Escent® reduces levels of mycotoxins in blood and improves health status and performance.

Reduction in blood from broilers: 

  • Deoxynivalenol: - 50%
  • Aflatoxin B1: - 40%

High concentration of mycotoxins in the feed (deoxynivalenol = 5,000 ppb and aflatoxin B1 = 20,000 ppb)