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ListShield™ is an all-natural, non-chemical antimicrobial preparation for controlling the foodborne bacterial pathogen Listeria monocytogenes. The active ingredients of ListShield™ are naturally occurring bacteriophages that selectively and specifically kill L. monocytogenes. ListShield™ is specifically designed for treating foods that are high risk for L. monocytogenes contamination. ListShield™ is ideal for use in HACCP programs that have identified L. monocytogenes control as a potential problem.

Functions: Anti-Microbial Agent

Ingredient Origin: Natural Origin

Labeling Claims: Clean Label, Halal, Kosher, Non-GMO, Organic, Preservative-free

Features: Cost Effective

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Identification & Functionality

Ingredient Origin
Food Ingredients Functions
Technologies

Features & Benefits

Food Ingredients Features
Bacteriophages

Bacteriophages (or phages) are nature’s way of destroying bacteria. A bacteriophage is a virus that is harmless to humans, animals, and plants but is very effective in killing bacteria. Specific phages kill specific bacteria. Bacteriophages are the most ubiquitous organisms on Earth, with their numbers estimated to be in the 1030 – 1032 range. They are naturally occurring and are commonly found almost everywhere, including in the water we drink and fresh foods we eat.

Applications & Uses

Applications

ListShield™ is marketed as a concentrated, aqueous, phage preparation that must be stored refrigerated (2-8°C) and then diluted with clean water prior to application. The packaging is labeled with clear instructions for use; bilingual instructions (e.g., English and Spanish) are available upon request. Usage instructions are laminated and can be easily displayed in the food-processing environment (e.g., attached to the walls in the food processing plant). An industrial sprayer may be required for large direct food applications. In cases of smaller bench-scale food applications, a handheld sprayer may be appropriate. • For direct food applications, the diluted working solution is typically applied directly on food surfaces by spraying at a concentration of approximately 1 - 2 mL per 250 sq. cm. of food product surface. • For foods with complex surfaces, application rate is usually 1 - 4 mL of the diluted working solution per lb of food. Contact Intralytix for suggestions regarding the application rate for your foods. Intralytix works closely with all customers to identify the optimal intervention spots and treatment regimens for each individual customer / production facility and provides an ongoing assistance with product use and applications

Regulatory & Compliance

ListShield™ is the choice for eliminating or significantly reducing contamination of food with specific pathogenic bacteria because it

Complies with FDA food additive regulations, for direct application to meat and poultry products that meet the ready-to-eat definition (21 CFR § 172.785). • Is FSIS-listed as safe and suitable for use as processing aid with no labeling requirements when applied to various ready-to-eat meat and poultry products (FSIS Directive 7120.1). • Is GRAS for direct application to fish and shellfish (including smoked varieties; e.g., smoked salmon), fresh and processed fruits, fresh and processed vegetables, and dairy products (including cheese) (GRN No. 528). • Is Health Canada approved for use on ready-to-eat meat and poultry, smoked salmon, fresh-cut apples, and long leaf lettuce (iLONO). • Is National Food Service of Israel approved as a food processing aid for the treatment of ready-toeat meat and poultry products (Ref: 70275202). • Is certified both Kosher and Halal. • Is OMRI listed (“organic”). • Does not contain preservatives. • Is cost effective and cost competitive. • Is effective under a wide range of food storage conditions (e.g. 2°C – 42°C)

Storage & Handling

Storage

ListShield™ should be stored refrigerated at 2-8°C in the original unopened container. Once opened, the contents should be used within 30 days. Precautions should be taken to not contaminate the content of the original container, when opening it and when measuring concentrated solution out of the container. The expiration date of ListShield™ may be sequentially extended in 6 month intervals if its potency is found to meet the specifications at the end of the expiration date. Intralytix can assist with potency determination if required. All packaging is recyclable and is specifically designed to withstand the moderately humid and cold environment recommended for storage