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GIVOCAL Calcium Glycerophosphate

1 of 1 products in this brand
Calcium is the most abundant mineral in the body. It is commonly associated with the formation and metabolism of bone. Over 99 percent of total body calcium is found as calcium hydroxyapatite (Ca10[PO4]6[OH]2) in bones and teeth, where it provides hard tissue with its strength. Calcium in the circulatory system, extracellular fluid, muscle, and other tissues is critical for mediating vascular contraction and vasodilatation, muscle function, nerve transmission, intracellular signaling, and hormonal secretion. Bone tissue serves as a reservoir for and source of calcium for these critical metabolic needs through the process of bone remodeling (Ross et al., 2011). The balance between bone resorption and deposition changes with age. In aging adults, particularly among postmenopausal women, bone breakdown exceeds formation, resulting in bone loss that increases the risk of osteoporosis over time (National Institute of Health, 2013).

Ingredient Name: Calcium Glycerophosphate (CGP)

Functions: Acidity Regulator, Mineral Source, Supplement

Physical Form: Powder, Solid

Technical Data Sheet

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Identification & Functionality

Mineral Type
Food Ingredients Functions
Pharma & Nutraceuticals Functions
CAS No.
27214-00-2, 126-95-4, 1336-00-1, 58409-70-4
EINECS No.
248-328-5, 204-813-3, 215-643-4, 261-240-1
Ingredients
Calcium Glycerophosphate (CGP)
Chemical Structure

GIVOCAL Calcium Glycerophosphate - Chemical Structure

Features & Benefits

Food Ingredients Features
Features

A “3 IN 1” SALT

  • It supplies calcium, glycerol and phosphorus.

Double Interest

  • This type of calcium salt has a physiologic and a metabolic interest due to the glycerophosphate, which is absent in inorganic calcium salts

A Superior Way

  • As part of nutraceuticals or health food, GIVOCALTM is a highly bioavailable source of calcium.

Scientific Evidences

  • Calcium glycerophosphate shows excellent absorption. Some other clinical studies show positive effects on bone and teeth development.

A Chelate

  • Glycerophosphate is an excellent vector for delivering calcium into the GI tract.
Health Claims For GIVOCAL
  • Calcium confributes fo normal blood clofting
  • Calcium contributes to normal energy-yielding metabolism
  • Calcium contributes to normal muscle function
  • Calcium contributes to normal neurotransmission
  • Calcium contributes to the normal function of digestive enzymes
  • Calcium has a role in the process of cell division and specialization
  • Calcium is needed for the maintenance ot normal bones
  • Calcium is needed for the maintenance of normal teeth

Applications & Uses

Food & Nutrition Applications
Applications
  • As an additive for dietetic purposes (substance for mineral contribution)
  • As an acid neutralizer in food and beverages
  • Used in chewing gum to give dental health benefits

Properties

Physical Form
Solubility
Molecular Weight
210.1
Taste
Neutral
Odor
Neutral
Appearance
Powder, Fine white powder
Soluble in
Water, Water
Insoluble in
Alcohols (Glycerol, Ethanol)
Typical Properties
ValueUnitsTest Method / Conditions
Density (at 20°C)0.55g/cm3
Theoretical calcium content19.05%
Water solubility (20°C)16.67g/L
Water solubility (hot water)1.43g/L
Calcium Content19.1%
Phosphorus Content14.6%
Calcium/Phosphorus ratio1.3

Regulatory & Compliance

Certifications & Compliance

Technical Details & Test Data

Bioavailability

Most calcium compounds given orally as a source of calcium are soluble in gastric acid but are converted mostly into insoluble calcium carbonate in the duodenum so that only a fraction of the calcium is available for absorption. Absorption of calcium salts therefore depends greatly on their solubility and stability in a wide pH range. A study on the capacity of acidity neutralization made on several calcium salts shows that GIVOCALTM has the smallest buffer power and then it is the best solubilized in the stomach. It also stays solubilized in the small intestine. These results were confirmed by an in vitro study made on the gastrointestinal model TIM-1 of TNO laboratory (The Netherlands) which compared the absorption of GIVOCALTM and calcium carbonate. With the same amount of calcium ingested (introduced into the system), GIVOCALTM permits a better absorption of calcium: 4 times more calcium is absorbed with GIVOCALTM than with calcium carbonate (internal results). Moreover, a recent study made on rats shows that, with the same amount of calcium ingested, GIVOCALTM has twice as less of calcium excretion than calcium carbonate (internal results). These results suggest that GIVOCALTM has a higher bioavailability than calcium carbonate. Other in vitro or in vivo studies show that GIVOCALTM allows a good assimilation of calcium by the bone tissue, has a cariostatic effect on teeth and shows a beneficial action on the nervous system (internal results).

GIVOCAL Calcium Glycerophosphate - Bioavailability

Packaging & Availability

Packaging Type
Packaging
  • 100 L cardboard drum with polyethylene bag low density lining filled with 50 kg net
  • 60 L cardboard box with polyethylene bag low density lining filled with 25 kg net