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Argireline® is considered a breakthrough in cosmetic technology as an alternative to well-known cosmetic procedures, topically targeting the same wrinkle-formation mechanism.

Lipochroman is powerful bioinspired antioxidant that protects biomolecules and cellular functions from oxidative stress damage and may aid in skin detoxification. As a result, it may help to reduce signs of aging and improve the skin appearance.

This hexapeptide improves the water flow from the epidermal basal layer to the stratum corneum to preserve and increase the rate of skin hydration. This hexapeptide increases in vitro the levels of Aquaporin 3 in keratinocytes, aquaglyceroporin responsible for ensuring the transport of water, thus contributing to maintaining skin barrier integrity. Naturality according to ISO 16128 - 49.98% natural origin content.

This hexapeptide targets specific areas of the face and body, which are vulnerable to the force of gravity and the deterioration with age. It increases the quantity of adipose tissue to obtain volume and curves where necessary. It stimulates PGC-1α expression, enhancing adipogenesis rate, and promotes lipid accumulation in the adipose tissue of targeted areas, increasing volume locally, as shown in vitro. Innovation Zone Best Ingredient Award: Silver, In-Cosmetics Asia 2011. Naturality according to ISO 16128 - 49.99% natural origin content.

A combination of several active ingredients incorporated in a new Lipotec’s delivery system that acts by different mechanisms to treat stretch marks already formed and also to prevent the appearance of new ones.

This glycoprotein protects the skin from dryness, thanks to its cryo-protective properties and strengthens the skin’s cohesion, thus reducing wrinkles. It stimulates the formation of collagen I and IV as well as elastin, as shown in vitro, thus restructuring the skin, which is protected under the most extreme cold conditions. Naturality according to ISO 16128 - 99.63% natural origin content.

Tetrapeptide that increases HSP70 (heat shock protein) levels in skin providing a protective shield, that confers cells a stress tolerance against everyday challenges and stressful stimuli. It helps skin to be more relaxed with a more vital appearance.

Liposomed tetrapeptide that regulates fibrillogenesis and the growth of collagen fibrils, improving skin cohesion for a more resilient and flexible appearance. It mimics the sequences of decorin, a small proteoglycan that binds to collagen fibers. It controls the diameter of the fibers, offering more consistency, and regulates fibrillogenesis to soften the skin, as showed in vitro studies. Naturality according to ISO 16128 - 98.02% natural origin content.

Biotechnological ingredient that helps minimize the accumulation of sebaceous lipids and strengthen the skin barrier function. The ingredient helps in naturally providing a healthy scalp with less itchiness, flakes and greasiness, while aids in daily managing dandruff-prone scalps.

Fermentation-based extract derived from clay microorganism that mimics the effects of clay on the skin; offers cleaner, smoother and more beautiful skin for all ethnicities and improved sense of well-being.

Combination of active peptides and proteins that provide an efficient treatment to restore the collagen levels of youth and mature skin, maintaining an adequate long-lasting collagen function that will ensure a healthy and youthful skin.

It helps inhibit glycation, vascular permeability and lipid accumulation, as showed in vitro, suggesting an improvement of the under-eye-region. The presence of eyebags and dark circles decreased in vivo. Naturality according to ISO 16128 - 99.96% natural origin content.

From marine biotechnology, it redefines both body and facial areas sensitive to sagging due to aging or insufficient physical activity such as double chin, abdomen, arms and thighs, by mimicking the effect of endurance exercise. It induces in vitro adiponectin release from adipose tissue that signals the skeletal muscle to enhance metabolism of type I muscle fibers. Innovation Zone Best Ingredient Award: Gold, In-Cosmetics 2014. Naturality according to ISO 16128 - 100% natural origin content.

Protection against pollution provided by a polymer with metal chelating properties and a potent free radical scavenger. pollushield™ functional ingredient defends the skin from the damage caused by heavy metals, particulate matter (PM) and other harmful substances found in big cities and polluted areas.

A holistic peptidic approach towards a double barrier function reinforcement to restore vulnerable skin to its original condition, more like that of our ancestors, in closer contact to nature. It promotes microbiota balance, as shown in vitro, helping to boost the skin’s own defense system. Naturality according to ISO 16128 - 99.49% natural origin content.

Shiitake mushroom-based extract providing a complete care of collagen in order to support a proper protein functionality leading to a firmer appearance of mature skin. Shows in vitro activity in increasing type I collagen and PLOD1 levels, as well as in reducing carbamylation process, responsible for the deterioration of skin proteins, such as collagen.

Reproage™ is a peptide that modulates the levels of microRNA-145 (miR- 145), involved in the regulation of epidermal differentiation. Reproage™ peptide may induce cell reprogramming to make the self-renewing ability of the epidermal basal layer last longer and help improve the skin complexion as a result.

xpertmoist® molecular film contains specific active ingredients with a high moisturising and regenerating effect that confers a pleasant feeling to the skin, even in extreme conditions. This occlusive improved delivery system has a great contact surface with the skin, minimising the TEWL and helping the active ingredients to penetrate more efficiently into the skin.

This tripeptide reinforces the skin’s natural immune system to prevent the risk of infection, thus preserving the balance of a healthy skin. It forms an immune barrier by stimulating the production of human-β- defensin -2 and -3, as showed in vitro studies, which are involved in the skin’s natural defense mechanism, to eliminate pathogens and combat microbial growth responsible for skin infections.

A complete care of eye contour that combats the three signs of tiredness and aging typical of this delicate skin area: dark circles, eyebags and wrinkles. Biotechnologically obtained, it reduces in vitro fluid extravasation while increases the degradation of bilirubin, promotes collagen I and elastin production and inhibits the formation of advanced glycation end products. Naturality according to ISO 16128 - 6.05% natural origin content.

Novel brightening active that evens out the skin tone for a fair and radiant complexion. In vitro efficacy showed its capacity to reduce both the production and the deposition of melanin in the skin by targeting key steps of pigmentation process: it regulates the gene expression of melanogenic signaling proteins, reduces tyrosinase levels and activity as well as diminishes melanin uptake by keratinocytes. Naturality according to ISO 16128 - 100% natural origin content.

Biotechnological ingredient that helps minimize the accumulation of sebaceous lipids and strengthen the skin barrier function. The ingredient helps in naturally providing a healthy scalp with less itchiness, flakes and greasiness, while aids in daily managing dandruff-prone scalps.

Ferment extract obtained through biotechnology from a radiation-resistant microorganism. Lumicease™ blue ingredient activates the epidermal photosensors and prepares, protects and repairs the skin from solar and artificial blue light-induced damage, helping minimize the main signs of digital and photoaging.

Lipomoist™ molecular films contain polysaccharides that form a continuous film on the skin. They offer an instant, long-lasting and excellent skin moisturization and provide a soft, light and pleasant sensation.

Organic stevia leaf-based extract, obtained using subcritical water extraction technology. Stevisse™ advanced botanical ingredient has a retinoid-like mechanism that minimizes the appearance of wrinkles for younger-looking skin.

Fungi-derived protease that enhances cell renewal specifically in the skin surface without the irritation and barrier damage. It shows similar activity of endogenous cathepsin D, with an optimal proteolytic effect below pH 5.0, for a controlled and adequate desquamation without side effects. Naturality according to ISO 16128 - 98.01% natural origin content.

It fights expression wrinkles by modulating muscle contraction in the pre-synaptic pathway and is specially addressed to topical formulations claiming to complement the injections of Botulinum Toxin Type A for enhanced anti-aging results. It addresses fundamental factors within muscle contraction in the pre-synaptic pathway to help attenuate expression wrinkles. As shown in vitro, it is able to inhibit neurotransmitter release at the pre-synaptic level, reducing the neuronal exocytosis and inhibiting muscle contraction. Innovation Zone Best Ingredient Award: Bronze, In-Cosmetics 2014. Naturality according to ISO 16128 - 99.48% natural origin content.

Nocturshape™ is a Exopolysaccharide (EPS) produced by a _ planktonic microorganism (Halomonas sp.) through biotechnology. Nocturshape™ blue ingredient takes advantage of the circadian rhythms and targets nocturnin in adipocytes, a protein involved in adipogenesis and lipid accumulation. It reduces thigh contour and smoothes skin relief, providing a general improvement of cellulite appearance.

Exopolysaccharide obtained through biotechnology which stimulates the synthesis of Hyaluronic Acid (HA), thus offering a plumping effect to the skin. It boosts in vitro the production of HA, the major compound of the extracellular matrix whose unbalance with aging leads to dehydration and loss of volume. Innovation Zone Best Ingredient Award: Bronze, In-Cosmetics 2012. Naturality according to ISO 16128 - 100% natural origin content.

This hexapeptide offers a new approach in the treatment of expression wrinkles through targeting muscles. It is a post-synaptic strategy that blocks agrin reducing the formation of AChR clusters, as showed in vitro, preventing neurotransmission and thus the contraction of the muscle. Naturality according to ISO 16128 - 99.49% natural origin content.