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Delisens™ peptide solution

1 of 1 products in this brand
Delisens™ peptide solution is a hexapeptide specifically formulated for sensitive skin and effectively addresses common issues associated with sensitivity. It provides relief from discomfort by alleviating tingling and itching sensations. Moreover, it aids in the recovery of the skin's barrier function, promoting its integrity. By increasing hydration levels, it helps prevent skin flaking and restores suppleness and softness to the skin, promoting a healthier and more comfortable complexion.

INCI Name: Acetyl Hexapeptide-49, Citric Acid

Functions: Soothing Agent

Benefit Claims: Anti-Inflammatory, Anti-Itching, Barrier Function Improvement, Hydrating, Non-Flaking, Reduces Tingling Sensations, Repairing, Restoring, Skin Barrier, Softening, Soothing, Suitable for Sensitive Skin, Suppleness

Knowde Enhanced TDS

Identification & Functionality

Carrier

Aqua,

Butylene Glycol,

Solvent-based

INCI Name

Acetyl Hexapeptide-49,

Citric Acid

Cosmetic Ingredients Functions

Soothing Agent

Technologies

Cosmetic Ingredients

Product Families

Cosmetic Ingredients — Functionals

Sensory Modifiers

Features & Benefits

Benefit Claims

Anti-Inflammatory,

Anti-Itching,

Barrier Function Improvement,

Hydrating,

Non-Flaking,

Reduces Tingling Sensations,

Repairing,

Restoring,

Skin Barrier,

Softening,

Soothing,

Suitable for Sensitive Skin,

Suppleness

Benefits
  • Down - regulates PAR - 2 activity
  • Attenuates neurogenic inflammation 
  • Helps barrier function recovery
Product Highlights

Science

  • Sensitive skin is a disturbing condition that can be induced by environmental factors (e.g. pollution, UV radiation, dryness), lifestyle factors (e.g. cosmetics, soaps), psychological factors or hormonal factors. Sensitive skin may worsen and give rise to acute or chronic inflammation disorders, where the threshold for pruritic stimuli causing itch sensation is lowered. PAR-2 activation (endogenously by trypsin-like serine proteases) amplifies the inflammation via the up-regulation of inflammatory mediators (such as interleukin (IL)-6 and IL-8) and induces transient receptor potential vanilloid-1 (TRPV1) sensitisation, leading to the release of inflammatory peptides calcitonin gene-related peptide (CGRP) and substance P (SP) also involved in neurogenic inflammation. Furthermore, activated PAR-2 delays barrier function recovery in damaged skin, due to, for example, scratching after contact with some chemicals, like allergens.
  • Delisens™ peptide down-regulates PAR-2 activity and as aresult CGRP, IL-6 and IL-8 release from skin cells, mediating neurogenic inflammation and therefore decreasing nagging pain sensation, discomfort and itching present in sensitive skin. It also helps to restore damaged tissue integrity, helping to the re-epithelisation and repair of damaged skin.

Applications & Uses

Markets

Personal Care

Applications

Personal Care — Beauty & Care

Skin Care

Application Format

Creams,

Leave On

Skin Care Applications

Hand Cream

Use Level
2.0 - 5.0%
Applications

Delisens™ peptide can be incorporated into daily care formulations and any specific treatments for sensitive skin where a soothing and repairing effect is needed.

Properties

Physical Form

Liquid,

Solution

Appearance
Transparent solution containing 0.025% Acetyl Hexapeptide-49.
Soluble in
Water
Properties

Delisens™ peptide ameliorates the discomfort of nagging pain and itch occurring in sensitive skin, besides restoring the damaged barrier integrity. In very dry sensitive skin, it increases hydration as well as improves scaling, smoothness and softness.