Knowde Enhanced TDS
Identification & Functionality
- Carrier
- INCI Name
- Ingredient Origin
- Cosmetic Ingredients Functions
- Technologies
- Product Families
Features & Benefits
- Benefit Claims
- Labeling Claims
- Product Benefits
- This vitamin E-like molecule can assist cells in the elimination of xenobiotics and free radicals from both the environment and the inner body. Captures three types of free radicals, ROS, RNS and RCS, protecting cells from irreversible DNA damage while preventing lipid peroxidation. It also modulates gene expression related to detoxification processes. Naturality according to ISO 16128 - 93.45% natural origin content.
- This antioxidant active ingredient prevents premature aging; its efficacy against oxidative stress is greater than other well-known agents such as Resveratrol, Vitamin E and Ferulic Acid.
- Triple protection: from ROS, RNS and RCS
- In & out detox
- Better skin appearance in 14 days
- Product Highlights
Science:
The skin is exposed to a myriad of xenobiotics that, together with other elements (e.g. UV radiation), generate reactive species. Reactive species can be based in oxygen (ROS), nitrogen (RNS) and carbonyl (RCS) and, at high levels, cause serious damage (e.g. lipid peroxidation, protein nitration and carbonylation), contributing to the appearance of aging signs. To prevent accumulation of xenobiotics and reactive species, cells rely on endogenous defense systems. Xenobiotics are metabolized through different phases that involve chemical transformation and excretion. Reactive species can be neutralized by small antioxidant or detoxified by a wide array enzymes.
Lipochroman™ molecule is a tocopherol analog that can capture reactive species and provide a detoxifying effect. When applied to the skin, antioxidative properties and parameters associated with aging were improved, while a depigmenting activity was also measured. Lipochroman™ AQO molecule is the water-soluble version of Lipochroman™ molecule, with enhanced stability and antioxidant profile thanks to its encapsulation in oil droplets.
Applications & Uses
- Markets
- Applications
- Skin Care Applications
- Sun Care Applications
- Use Level
- 1 - 5 %
Properties
- Appearance
- White to light yellow liquid emulsion
- Typical Properties
| Value | Units | Test Method / Conditions | |
| Natural Origin | 93.5 | % | ISO 16128 |
Regulatory & Compliance
- Certifications & Compliance
Technical Details & Test Data
- In Vitro Efficacy
- Skin cells were protected from the genotoxic effect of pollutants and UV
- Increasing internal antioxidative defenses Removing foreign substances out of the skin.
- Preservation of essential oils in formulation
- In Vivo Efficacy
Cutaneous Antioxidative Capacity and Improvement of Aging Signs:
20 women (33-57 years old) applied a cream* with 0.05% Lipochroman™ molecule to half face and a placebo cream on the other half, twice a day for 28 days.
- Better antioxidative properties: Recovery of elasticity and improvement in appearance of wrinkles and spots.
Helping to improve the skin tone
31 women (18-44 years old) applied a cream with 0.05% Lipochroman™ molecule to half face and a placebo cream on the other half. After 14, 28 and 56 days, the melanin index was measured by mexametry.
Dark spots were less visible suggesting a fairer complexion
