Lipochroman™ Molecule

Identification & Functionality

INCI Name

Dimethylmethoxy Chromanol

Ingredient Origin

Natural Origin

Cosmetic Ingredients Functions

Antioxidant,

Protective Agent

CAS No.

83923-51-7

Technologies

Cosmetic Ingredients

Product Families

Cosmetic Ingredients — Cosmetic Actives

Skin Actives

Features & Benefits

Benefit Claims

Age & Dark Spot Reduction,

Anti-Aging,

Anti-Pollution,

Antioxidant Properties,

DNA Protection,

Detoxifying,

Encapsulated Actives,

Even Skin Tone,

Free Radical Scavenging,

Glowing Effect,

Improves Skin Appearance,

Oxidation Protection,

Protection From Environmental Damage,

Skin Protection,

UV Protection

Labeling Claims

Clean at Sephora,

Credo Clean Standard,

Halal,

Natural,

Naturally Derived,

Sustainable,

Ulta Beauty's Conscious Beauty

Product Highlights

Science:

 

The skin is exposed to a myriad of xenobiotics that, together with other elements (e.g. UV radiation), generate reactive species. Reactive species can be based in oxygen (ROS), nitrogen (RNS) and carbonyl (RCS) and, at high levels, cause serious damage (e.g. lipid peroxidation, protein nitration and carbonylation), contributing to the appearance of aging signs. To prevent accumulation of xenobiotics and reactive species, cells rely on endogenous defense systems. Xenobiotics are metabolized through different phases that involve chemical transformation and excretion. Reactive species can be neutralized by small antioxidant or detoxified by a wide array enzymes.

 

Lipochroman™ molecule is a tocopherol analog that can capture reactive species and provide a detoxifying effect. When applied to the skin, antioxidative properties and parameters associated with aging were improved, while a depigmenting activity was also measured. Lipochroman™ AQO molecule is the water-soluble version of Lipochroman™ molecule, with enhanced stability and antioxidant profile thanks to its encapsulation in oil droplets.

Product Benefits

• Triple protection:  from ROS, RNS and RCS
• In & out detox
• Better skin appearance in 14 days

Applications & Uses

Markets

Personal Care

Applications

Personal Care — Beauty & Care

Bath & Shower,

Color Cosmetics,

Hair Care,

Skin Care,

Sun Care

Application Format

Bar,

Creams,

Gel,

Leave On,

Lotions,

Masks,

Oil,

Rinse Off,

Serum,

Stick

Bath & Shower Applications

Bath Oil,

Scrub

Color Cosmetic Applications

Glitters

Hair Care Applications

Hair Conditioner,

Hair Serums,

Hair Treatment & Repair,

Shampoos & Rinses

Skin Care Applications

Anti-Aging Products,

Body Oil,

Face Lotion,

Facial Gel,

Facial Mask,

Healthy Aging Products,

Make Up Remover,

Massage Products,

Moisturizers,

Skin Conditioner Mousse,

Skin Serums

Sun Care Applications

After Sun Products,

Sunscreen Gel,

Sunscreen Lotion,

Sunscreen Stick

Use Level

0.01 - 0.05 %

Properties

Physical Form

Powder,

Solid

Appearance

Light yellow to brown powder

Typical Properties

	Value	Units	Test Method / Conditions
Natural Origin	93.5	%	ISO 16128

Regulatory & Compliance

Certifications & Compliance

CFDA Compliant (China),

Halal,

ISO 16128

Technical Details & Test Data

In Vitro Efficacy

• Skin cells were protected from the genotoxic effect of pollutants and UV
• Increasing internal antioxidative defenses Removing foreign substances out of the skin.
• Preservation  of essential oils in formulation

 

In Vivo Efficacy

Cutaneous Antioxidative Capacity and Improvement of Aging Signs:

20 women (33-57 years old) applied a cream* with 0.05% Lipochroman™ molecule to half face and a placebo cream on the other half, twice a day for 28 days.

 

 

 

Better antioxidative properties: Recovery of elasticity and improvement in appearance of wrinkles and spots.

 

Helping to improve the skin tone

31 women (18-44 years old) applied a cream with 0.05% Lipochroman™ molecule to half face and a placebo cream on the other half. After 14, 28 and 56 days, the melanin index was measured by mexametry.

Dark spots were less visible suggesting a fairer complexion