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MacDerma™ MA is extracted from the bitter almond and is an alpha hydroxyl acid (AHA). Alpha hydroxy acids speed up the cellular turnover rate, ridding the skin of dead skill cells that enhance the natural creases in skin and dull the complexion. MacDerma™ MA is the largest aromatic AHA. Since it has a large molecular size it’s less of an irritant, making it even more popular than glycolic acid in skin care. It is suitable for all skin types and complexions.

INCI Name: Aqua, Mandelic Acid

Functions: Anti-Acne Agent, Anti-Microbial Agent, Exfoliant (Chemical)

Ingredient Origin: Synthetic

Labeling Claims: 1,4-Dioxane-free, Allergen-free, Animal Products-free, BSE-free, Bisphenol A-free, Butylated Hydroxyanisole-free, CMR Substances-free, Clean at Sephora, Credo Clean Standard, Formaldehyde-free, Fragrance-free, Gluten-free, Glycol ether-free, Hormones-free, Latex-free, Nanomaterials-free, Nitrosamines-free, Non-GMO, Non-Phenolic, Not Listed In California Proposition 65, Not Tested on Animals, Palm Oil-free, Palm free, Paraben-free, Petrochemical-free, Phthalates-free, Silicone-free, Soy-free, Sulfate-free, TSE-free, Talc-free, Ulta Beauty's Conscious Beauty

Benefit Claims: Anti-Acne, Anti-Bacterial, Antimicrobial, Exfoliating, Solubilizing, Water Soluble

Knowde Enhanced TDS

Identification & Functionality

Country of Origin
Ingredient Origin

Features & Benefits

Key Features
  • Anti-Acne
  • Anti-Bacterial
  • Reduced Photosensitivity
  • Exfoliant

Applications & Uses

Application Format
Use Level
4 - 10%
Product Applications
  • Chemical Peels
  • Face Washes
  • Cleaners
  • Moisturizers
  • Eye Lift Creams

Properties

Physical Form
Appearance
White crystalline powder
Soluble in
Water, Ether
Typical Properties
ValueUnitsTest Method / Conditions
Assaymin. 99%
Melting Point117 - 121°C
Chemical Composition
ValueUnitsTest Method / Conditions
Mandelic Acid Contentmin. 99%
Water Contentmax. 1%
Heavy Metals
ValueUnitsTest Method / Conditions
Lead Contentmax. 20ppm

Regulatory & Compliance

Technical Details & Test Data

Efficacy Testing

Effect of Mandelic Acid on Skin Photosensitivity

MacDerma™ MA - Efficacy Testing

Result: Mandelic Acid induces less photosensitivity than glycolic acid

Twenty volunteers, ages 25-35 were treated with 10% acids for four weeks and exposed to UVB irradiation. Percent photosensitivity was calculated from the erythema index

 

In Vivo testing of effect of Mandelic Acid on Acne.

MacDerma™ MA - Efficacy Testing - 1

Twenty-two subjects received 35% glycolic acid peels or 20% salicylic-10% mandelic acid peels every 2 weeks.

Result:  The total acne score improved 52.3% in the salicylic-mandelic peel group vs 27.3% in the glycolic acid peel group (P<0.001)

Storage & Handling

Shelf Life
2 years
Storage Conditions

Store at ambient conditions.