Nuovo-Proline-16 - McKinley Resources - Synthetic

Identification & Functionality

Chemical Name: Dipalmitoyl Hydroxyproline
Country of Origin: China
INCI Name: Dipalmitoyl Hydroxyproline,
Hydroxyproline Palmitamide,
Palmitic Acid
Ingredient Origin: Synthetic
Cosmetic Ingredients Functions: Anti-Aging Agent,
Anti-Wrinkle Agent,
Antioxidant,
Moisturizing Agent,
Toning Agent
CAS No.: 41672-81-5
EC No.: 255-490-0
Technologies: Cosmetic Ingredients
Product Families: Cosmetic Ingredients — Cosmetic Actives
Skin Actives
Cosmetic Ingredients — Functionals
Conditioners & Emollients

Features & Benefits

Benefit Claims: Anti-Aging,
Anti-Wrinkle,
Antioxidant Properties,
Collagen Boosting,
Even Skin Tone,
Moisturizing,
Skin Tightening,
Toning
Labeling Claims: 1,4-Dioxane-free,
BSE-free,
Bisphenol A-free,
Butylated Hydroxyanisole-free,
Butylated Hydroxytoluene (BHT)-Free,
CMR Substances-free,
Clean at Sephora,
Credo Clean Standard,
Formaldehyde-free,
Fragrance allergen-free,
GMO-free,
Gluten-free,
Glycol ether-free,
Hormones-free,
Latex-free,
Nanomaterials-free,
Nitrosamines-free,
Non-Phenolic,
Not Listed In California Proposition 65,
Not Tested on Animals,
Palm Oil-free,
Palm free,
Paraben-free,
Petrochemical-free,
Phthalates-free,
SVHC Chemicals-free,
Silicone-free,
Soy-free,
Sulfate-free,
TSE-free,
Talc-free,
Ulta Beauty's Conscious Beauty,
VOC-free

Applications & Uses

Markets: Personal Care
Applications: Personal Care — Beauty & Care
AP/Deo,
Color Cosmetics,
Skin Care,
Sun Care,
Treatment Products
Application Format: Balm,
Creams,
Gel,
Leave On,
Lotions,
Masks,
Ointments,
Powder,
Rinse Off,
Roll On,
Spray,
Stick
Color Cosmetic Applications: Foundation,
Lip Balm,
Lipstick
Fragrances & Perfume Applications: Fragrances & Perfumes
Skin Care Applications: Around Eye Cream,
Body Firming Lotion,
Facial Cleanser,
Facial Mask,
Facial Moisturizer,
Skin Toners,
Tanning Products
Sun Care Applications: Self Tanning,
Sunscreen Cream,
Sunscreen Lotion
Treatment Product Applications: Scar Treatment,
Varicose Vein Treatment
Use Level: 0.1 - 1 %

Properties

	Value	Units	Test Method / Conditions
Dipalmitoyl Hydroxyproline Content	min. 56	%	—
Hydroxyproline Palmitamide Content	max. 44	%	—
Palmitic Acid Content	max. 5	%	—

	Value	Units	Test Method / Conditions
Assay (DPHP)	min. 56	%	—

Regulatory & Compliance

Chemical Inventories: AICS (Australia),
EINECS (EU),
ENCS (Japan),
IECSC (China),
NDSL (Canada),
NZIoC (New Zealand),
PICCS (Phillipines),
TSCA (USA)

Technical Details & Test Data

Efficacy Testing Information: In-vivo Testing of Effect on Wrinkles (0.5% Nuovo-Proline-16™):

Method: Skin topography was measured as a density sequence using the Visia 3D imaging system. The images are before anti-aging treatment and eight weeks after anti-aging treatment using 0.5% Nuovo-Proline-16™. A significant improvement in contrast depth contours is recorded in the test area.

Wrinkle depth decreased, evidenced by density reduction of 75%

In-vivo Testing of Facial Wrinkle Reduction (0.5% Nuovo-Proline-16™):

Method: Wrinkle depth was measured in two dimensions, using 0.5% Nuovo-Proline-16™ after eight weeks. The dark line represents the initial wrinkle depth 3.2270 (mm) and the light line 3.8780 (mm) represents depth after eight weeks. The graph shows the shallower wrinkle valley after treatment.

Wrinkle depth was reduced by 16.8%

Storage & Handling

Nuovo-Proline-16™