RenoFlavone™

Identification & Functionality

Active Component

Genistein Phosphate

Ingredient Name

Fermented Soy Extract

Pharma & Nutraceuticals Functions

Supplement

Technologies

Food Ingredients,

Pharmaceuticals & Nutraceuticals

Product Families

Pharmaceuticals & Nutraceuticals — Nutraceuticals & Supplements

Phytochemicals & Plant Extracts,

Supplements & Functional Ingredients

Food Ingredients — Nutrition & Fortification

Functional Ingredients,

Phytochemicals

Features & Benefits

Benefit Claims (Health)

Improves Cognitive Health,

Improves Menstrual Health,

Kidney Health,

Metabolic Wellness,

Microbiome Balance,

Reduces Vascular Inflammation,

Support's Women Health,

Supports Cardiovascular health,

Supports Healthy Aging

Labeling Claims

Ethylene Oxide-free,

GMO-free,

Gluten-free,

Vegan

Food Ingredients Features

Excellent Bioavailability,

Improved Blood Circulation,

Improved Bone Health,

Prevents Kidney Problems,

Rapid Absorption

Product Highlights

• 100,000X aqueous solubility
• 3.7X oral bioavailability
• Scientifically proven efficacy
• Unique absorption mechanism
• 2023 US FDA New Dietary Ingredient
• Proven Efficacy

Applications & Uses

Markets

Food & Nutrition,

Healthcare & Pharma

Applications

Healthcare & Pharma — Drug Delivery & Care Solutions

Oral

Food & Nutrition — Nutrition & Well Being

Nutraceuticals & Supplements

Dosage Form

Capsules,

Gummies,

Tablets

Food & Nutrition Applications

Dietary Supplements,

Nutraceuticals

Use Level

40 - 80 mg

Properties

Physical Form

Powder

Solubility

Water Soluble

Appearance

White to pale yellow fine powder

Chemical Properties

	Value	Units	Test Method / Conditions
Water-soluble Isoflavone Derivatives	min. 70	%	QA_Q02_AH1,HPLC
Arsenic Content	max. 2	ppm	MOHWH0014.03

Physical Properties

	Value	Units	Test Method / Conditions
Loss on Drying	max. 6	%	QA-Q01-AH1

Microbiological Values

	Value	Units	Test Method / Conditions
Yeast & Molds Count	max. 102	cfu/g	MOHWM0008.01
Total Aerobic Plate Count	max. 103	cfu/g	MOHWM0014.01
Salmonella	Negative	/25g	MOHWM0025.01
Escherichia Coli	Negative	/g	MOHWM0023.02
Enterobacteria	max. 10	cfu/g	MOHWM0028.00

Heavy Metals

	Value	Units	Test Method / Conditions
Lead Content	max. 20	ppm	MOHWH0014.03

Regulatory & Compliance

Certifications & Compliance

FDA Compliant,

GMP,

Generally Recognized As Safe (GRAS),

New Dietary Ingredients (NDI)

Technical Details & Test Data

Pharmacokinetic Profile

Mean plasma concentration-time profiles of genistein in rats after oral adminstration of native genistein and RenoFlavone™ at 3.7 u mol/kg bw. Data are mean  SE (n = 4).

Animal Study Improve Menopausal Bone Health

Osteoprotective effect of RenoFlavone™, a derivative of genistein with high bioavailability, in ovariectomized rats. Mi ovarietomized rats. Bet of plate and entral met wip (15.2 umol/kg bw/day) after 12-week treatment. Data are mean ‡SD, n = 6. Value are mean‡SEM. ** p < 0.01. RenoFlavone™ vs placebo group (paired t-test).

Human study Relieve menstrual discomfort

A randomized controlled trial of RenoFlavone™ in the treatment of primary dysmenorrhea. Effects of RenoFlavone™ (20 mg/ day) and placebo on menstrual pain score (Short form McGill pain questionnaire score, SF-MPQ) in first month (The trial is ongoing). Value are mean  SEM, n = 40. Comparison of changes between the study groups (chi-square test). Significance of double star symbol is *** p< 0.001.

Packaging & Availability

Packaging Type

Bags

Storage & Handling

Shelf Life

3 years

Storage and Shelf Life Conditions

Store in aluminum bag at controlled room temperature for 3 years.