Knowde Enhanced TDS
Identification & Functionality
- Active Component
- Ingredient Name
- Pharma & Nutraceuticals Functions
Features & Benefits
- Benefit Claims (Health)
- Labeling Claims
- Food Ingredients Features
- Product Highlights
- 80,000X aqueous solubility
- 8.2X Superiod Bioavailability
- Scientifically proven efficacy
- Unique absorption mechanism
- Improved the maximum plasma level of Luteolin in systemic circulation by approximately 21.5 times commerical products (2150%)
Applications & Uses
- Applications
- Food & Nutrition Applications
- Use Level
- 100 - 200 mg
Properties
- Physical Form
- Appearance
- Yellow brown fine powder
- Chemical Properties
- Physical Properties
- Microbiological Values
- Heavy Metals
| Value | Units | Test Method / Conditions | |
| Water-soluble Luteolin Derivatives | min. 15 | % | QA_Q02_AH1,HPLC |
| Arsenic Content | max. 2 | ppm | MOHWH0014.03 |
| Value | Units | Test Method / Conditions | |
| Loss on Drying | max. 10 | % | QA-Q01-AH1 |
| Value | Units | Test Method / Conditions | |
| Yeast & Molds Count | max. 102 | cfu/g | MOHWH0008.01 |
| Total Aerobic Plate Count | max. 103 | cfu/g | MOHWH0014.01 |
| Salmonella | Negative | /25g | MOHWH0025.01 |
| Escherichia Coli | Negative | /g | MOHWH0023.02 |
| Enterobacteria | max. 10 | cfu/g | MOHWH0028.00 |
| Value | Units | Test Method / Conditions | |
| Lead Content | max. 20 | ppm | MOHWH0014.03 |
Regulatory & Compliance
- Certifications & Compliance
Technical Details & Test Data
- Pharmacokinetic Profile
Mean plasma concentration-time profiles of hesperetin in rats after oral adminstration of native hesperidin and RenoCidin™ at 22.8 u mol/kg bw. Data are mean SE (n = 4).- Animal Study Support Cognitive & Memory Health
Effects of luteolin on LPS-induced cognitive learning and spatial memory impairment in Morris water maze tests. The swimming and the escape latency of mice during the Morris water maze tests. Mice received luteolin (120 mg/kg/ day) via the intragastric route for 14 days and received LPS (250 pg/kg/day) via an intraperitoneal injection for 7 days before the Morris water maze test started. A two-way ANOVA showed a difference between the Con or Lut vs. LPS (p< 0.0001).
- Human Study Manage Gout and Uric Acid
Effects of luteolin on uric acid in serum of potassium oxonate (PO)-induced hyperuricemia mice. Data represent mean ‡ SEM for 10 mice. Mice were administrated with luteolin (100 mg/kg/day for 7 days, n=10) or treated with only vehicle (saline 10 ml/kg/day, n=10) as model group after PO-induced hyperuricemia in mice. ##p< 0.01 compared with normal group: **p< 0.01 compared with model group (independent samples t-test).
Packaging & Availability
- Packaging Type
Storage & Handling
- Shelf Life
- 3 years
- Storage and Shelf Life Conditions
Store in aluminum bag at controlled room temperature for 3 years.